Geneology International

Tag: effects

  • Health Tips Fitness Know How Exercise And Workout Side Effects

    Health Tips Fitness Know How Exercise And Workout Side Effects

    Wellness Ideas : कोविड के बाद वर्क फ्रॉम होम का ट्रेंड बढ़ा है. घर में बैठे-बैठे फिजिकल एक्टिविटी पर फुल स्टॉप सा लग गया है. इसका असर यह हुआ है कि पूरा रूटीन ही बिगड़ा हुआ है. इससे सेहत (Wellness) को भी कई तरह की परेशानियां हो रही हैं. इन सबके बीच जो सबसे अच्छी बात है, वह यह कि आजकल लोग हेल्थ और फिटनेस को लेकर काफी अवेयर भी हुए हैं. एक्सरसाइज, वर्कआउट और योग उनकी दिनचर्या का हिस्सा है लेकिन क्या आप जानते हैं कि अगर सही तरह से वर्कआउट न किया जाए तो यह फायदे की जगह नुकसान (training aspect consequences) भी पहुंचा सकता है. आइए जानते हैं..

     

    योग करना

    प्राचीनकाल से ही योग हमारी लाइफ का हिस्सा रहा है. इससे न सिर्फ शरीर बल्कि दिमाग भी एक्टिव रहता है. लेकिन अगर इसे गलत तरीके से किया जाए तो इसके नुकसान भी हो सकते हैं. योग में कुछ चीजें नहीं करने की सलाह दी गई हैं. जैसे- हर किसी को शीर्षासन नहीं करना चाहिए. ऐसे लोग जिन्हें किसी तरह की पेट की बीमारी रही हो, उन्हें दबाव डालने वाले योग से परहेज करने को कहा गया गया है. ओम का उच्चारण भी कुछ परिस्थितियों में मना होता है. ऐसे में अगर आप योग करते हैं तो एक सही प्रशिक्षक से मदद लें.

     

    ट्रेडमिल पर चलना

    आजकल हर किसी के पास ट्रेडमिल या जिम वाली साइकिल है. इन मशीनों पर अचानक या जरूरत से ज्यादा चलना नुकसानदायक हो सकता है. आजकल कई ऐसे केस आ रहे हैं, जब ट्रेडमिल पर चलते-चलते ही हार्ट अटैक आ जाता है. ऐसा तब ज्यादा हो सकता है, जब वजन ज्यादा हो और बहुत दिनों बाद अचानक से एक्सरसाइज की जा रही हो. हाई बीपी और शुगर अनकंट्रोल की स्थिति में ऐसा होता है. इसका एक कारण यह भी होता है कि ट्रेडमिल या जिम साइकिलिंग हमेशा बंद जगह पर होती है, इससे पर्याप्त ऑक्सीजन नहीं मिल पाता और सेहत के लिए खतरा बन जाता है.

     

    रनिंग या जॉगिंग

    रनिंग या जॉगिंग सबसे अच्छी एक्सरसाइज में से एक है. इसका फायदा पूरी बॉडी को होता है लेकिन अगर आप किसी दिन अचानक से दौड़ना शुरू कर देते हैं तो यह फायदेमंद नहीं होता है. 40 साल के बाद, बढ़े वजन के साथ अचानक दौड़ना या जॉगिंग हड्डियों के साथ दिल के लिए नुकसानदायक होता है. रोजाना वर्कआउट करने वाले, खिलाड़ी या आर्मी जवान रोजाना कई-कई किलोमीटर तक दौड़ते, इसका फायदा उन्हें मिलता है. यह उनका रूटीन होता है और इसके लिए वे वॉर्मअप, स्ट्रेचिंग, सही रूटीन और सही तरीके से दौड़ने की ट्रेनिंग लेते हैं. यह भी फैक्ट है कि दौड़ते या जॉगिंग करने के दौरान शरीर का पूरा वजन एक साथ पैरों पर पड़ता है. इसका नुकसान कड़क हो चुकी मसल्स और दिल को हो सकता है. दौड़ने की शुरुआत करनी है तो सबसे पहले सही शूज चुने और लगातार तेज चलकर प्रैक्टिस करें. पहले 5 मिनट के दौड़ से शुरुआत करें और फिर धीरे-धीरे इसे आगे ले जाएं.

     

    बाकी एक्सरसाइज

    जुंबा, एरोबिक्स, रस्सी कूदना, मार्शल आर्ट जैसी एक्टिविटीज को कभी भी अचानक से शुरू न करें. इसका नुकसान हड्डियों और मसल्स पर तो होता ही है, रीढ़ को भी जोखिम में डाल देता है. इसके साथ ही हार्ट, लिवर जैसे अंग भी प्रभावित होते हैं. ओवरवेट हैं तो सबसे पहले किसी एक्सरपर्ट से सही एक्सरसाइज चुने और फिर आगे बढ़ें.

     

    यह भी पढ़ें

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  • High doses of cannabidiol may increase the effects of THC in edible cannabis products

    High doses of cannabidiol may increase the effects of THC in edible cannabis products

    Opposite to some prevalent promises, a study led by Johns Hopkins Medicine scientists found that rather significant doses of cannabidiol (CBD) may possibly maximize the adverse outcomes of delta-9-tetrahydrocannabinol (THC), the principal energetic component in cannabis that can bring about a temper alteration or a “superior” feeling. The conclusions exhibit that in edible cannabis products and solutions, CBD inhibits the rate of metabolism, or breakdown, of THC, which might outcome in much better and for a longer time drug consequences.

    The benefits of the study, posted Feb. 13 in JAMA Network Open up, uncovered that the greatest volume of THC calculated in participants’ blood samples was virtually two times as superior right after consuming a brownie containing THC with CBD than soon after having a brownie with only THC, even though the dose of THC in each individual brownie (20 mg) was the similar. In addition, the optimum amount of money of 11-OH-THC (a metabolic byproduct of THC that provides drug consequences identical to THC) was 10-fold bigger after consuming the brownie with the substantial CBD extract in contrast with the just one made up of superior THC extract.

    The function examined the pharmacokinetics (absorption and elimination of a drug by the physique) and pharmacodynamics (the body’s response to a drug) involving hashish extracts that different with regard to THC and CBD concentrations.

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    The reality that THC and CBD had been orally administered was very significant for the examine, and performed a substantial part in the behavioral results and drug interactions we saw.”

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    Austin Zamarripa, Ph.D., postdoctoral research fellow at the Johns Hopkins College Faculty of Drugs and the study’s direct writer

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    Prior managed human reports analyzing these interactions have predominantly administered THC and CBD by inhalation or intravenously, or have not administered them at the exact time. For this reason, much of the current information concerning interactions concerning THC and CBD may possibly not utilize to edible cannabis products and solutions these types of as baked products, candies and gummies, which get metabolized in the intestine and liver.

    “In general, we saw more powerful subjective drug outcomes, greater impairment of cognitive [thinking] and psychomotor [moving] capability and increased boost in coronary heart charge when the similar dose of THC was provided in a superior CBD hashish extract, when compared with a large THC extract with no CBD,” states Zamarripa.

    The new study, which analyzed every style of cannabis extract and a placebo within just the exact topics alternatively than making use of distinct men and women for every drug sort, was performed from January 2021 to March 2022 at the Behavioral Pharmacology Analysis Unit at Johns Hopkins Bayview Professional medical Heart. The scientists recruited 18 grownup members (11 gentlemen and 7 gals) who had not used hashish for at the very least 30 days prior to beginning the review.

    Research volunteers took part in three sessions, every divided by at the very least a person week. In every single session, participants consumed a brownie made up of both 20 mg of THC, 20 mg of THC and 640 mg of CBD, or no THC or CBD (placebo). Neither the contributors nor the investigators realized in progress what was in the brownie that members ate on a presented session. Individuals were also offered a drug cocktail consisting of five cytochrome (CYP) probe medicines (100 mg caffeine, 25 mg losartan, 20 mg omeprazole, 30 mg dextromethorphan, and 2 mg midazolam) 30 minutes right after taking in each and every brownie. These medication will support the scientists figure out how CBD and THC have an impact on how participants’ bodies metabolize other usually applied drugs and nutritional dietary supplements (in analyses that will be published independently).

    To create a foundation for comparison, baseline blood samples were gathered from all members prior to every single session, alongside with their essential indicators (coronary heart level and blood stress), and actions of cognitive and psychomotor general performance. Contributors supplied blood and urine samples at timed intervals for 12 hours and then again about 24 several hours immediately after drug dosing was accomplished. Self-described drug consequences have been calculated utilizing the Drug Influence Questionnaire (DEQ), a standardized instrument utilised to assess areas of subjective encounters just after getting presented a psychoactive drug like THC or cannabis.

    Though contributors professional the usual consequences generated by hashish with both of those the CBD and THC extracts, there were notable distinctions in between the two, which are most likely the final result of the greater focus of THC and 11-OH-THC in the blood after the CBD extract was consumed.

    Using the DEQ tool, participants rated subjective drug effects with a scale from to 100, with being “not at all afflicted” and 100 remaining “very afflicted.” Amid the subjective ratings, individuals professional increased will increase in in general drug outcomes (59 [THC] vs. 73 [THC + CBD]), unpleasant drug results (20 [THC] vs. 39 [THC + CBD]), emotion unwell (12 [THC] vs. 26 [THC + CBD]), dry/purple eyes (16 [THC] vs. 29 [THC + CBD]), and problems carrying out regime tasks (30 [THC] vs. 47 [THC + CBD]). Immediately after ingesting the brownie with the significant CBD hashish extract, individuals showed substantially far more impairment in overall performance on assessments of memory and notice compared with when they consumed the brownie with the significant THC extract.

    Consuming the superior CBD extract brownie also resulted in a better boost in heart rate, from a 10 beats for each minute raise from baseline [THC] to a 25 beats for every minute increase from baseline [THC + CBD]. The placebo brownie did not increase the subjective drug outcome scores or change the efficiency on any cognitive or psychomotor responsibilities.

    “We have demonstrated that with a relatively large oral dose of CBD [640 mg] there can be considerable metabolic interactions concerning THC and CBD, these types of that the THC consequences are much better, more time-lasting, and have a tendency to reflect an enhance in undesirable adverse consequences,” states Ryan Vandrey, Ph.D., professor of psychiatry and behavioral sciences at the Johns Hopkins College University of Drugs and the study’s senior author.

    Vandrey observed that an additional of his team’s current scientific tests found that CBD merchandise are not always properly labeled. “Our new research suggests that it’s crucial for individuals to be conscious that if they are heading to get a substantial-dose CBD extract, they also have to have to be aware about interactions with other drugs. Persons need to explore with their medical professional whether or not they must look at dose adjustments of THC and other drugs if they are also taking CBD,” claims Vandrey.

    The researchers say that long term research are necessary to additional understand the effects of CBD and THC dose, relative focus, frequency of use, and person wellness dissimilarities on how our bodies metabolize commonly applied drugs. This kind of investigation is required to advise clinical and regulatory final decision-making concerning the therapeutic and nontherapeutic use of cannabis items.

    In addition to Zamarripa and Vandrey, other researchers who contributed to the study involve Tory Spindle, Renuka Surujunarain and Elise Weerts from the Johns Hopkins College Sumit Bansal from the College of Washington Jashvant D. Unadkat from the College of Washington and the Centre of Excellence for Pure Item Drug Conversation Exploration and Mary F. Paine from Washington Point out College and the Center of Excellence for Natural Products Drug Interaction Exploration.

    Supply:

    Journal reference:

    Austin Zamarripa, C., et al. (2023) Assessment of Orally Administered Δ9-Tetrahydrocannabinol When Coadministered With Cannabidiol on Δ9-Tetrahydrocannabinol Pharmacokinetics and Pharmacodynamics in Healthier Grownups: A Randomized Scientific Demo. JAMA Community Open up. doi.org/10.1001/jamanetworkopen.2022.54752.

  • Verti CBD Gummies REVIEWS [Scam OR Legit] Shark Tank Exposed Side Effects?

    Verti CBD Gummies REVIEWS [Scam OR Legit] Shark Tank Exposed Side Effects?

    To decrease agony, combat melancholy, relieve inflammation, raise the mind, and avert diseases, we generally acquire nutritional dietary supplements that work effectively but may well result in adverse reactions. 

    It is totally frustrating when you consider supplements to enhance your health and end up struggling some really serious aspect effects and detrimental reactions. 
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    Verti CBD Gummies, according to medical professionals and health-related practitioners, are a remarkable wellness-boosting treatment that efficiently supports nutritious perfectly-currently being and encourages an sickness-free system.

    Fairly than antibiotics, prescription drugs, and health supplements, CBD gummies are the optimal answer to combat health conditions and unwell health disorders. 
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    CBD gummies are expense-helpful and properly-researched medications that assist to downplay the outcomes of a variety of health care ailments although concurrently developing a very well-crafted physique. 

    These chewy gummies have been demonstrated to increase total health when lowering the likelihood of diagnosable actual physical health concerns and easing the indicators of psychological wellness imbalances.

    Wellness gurus assert that Verti CBD Gummies are a great solution that helps to increase all bodily systems and avert sicknesses that could be harmful to your very well-becoming.

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    CBD gummies start out to do the job in incredible ways and present you with a ailment-no cost body in each element following becoming absorbed into blood vessels. These have been produced and analyzed extensively in 3rd-celebration labs.

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    Healthcare industry experts imagine that the ideal doses of CBD gummies can proficiently take care of a wide array of ailments and prevent their advancement and progress way too. 
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    Verti CBD Gummies are now remaining suggested by medical doctors to people who want to attain excellent wellbeing and fitness with out any trouble. 

    These gummies have a range of pros for patients’ wellbeing and people whose health and fitness is declining.

    Quick to try to eat and a breath-getting resolution, CBD chewable candies will deal with all of your health and fitness and fitness troubles devoid of triggering any damage.

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    The endocannabinoid method (ECS) is a mobile system that handles the organic systems of the system, and other receptors. 

    ECS interacts with neurotransmitters and aids in sign transmission from a single cell to one more.

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    Verti CBD Gummies are formed in 3rd get together labs below the supervision of licenced health care professionals. These are derived from medicinal cannabis, which has loads of therapeutic and remedial attributes. 

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    Normal ingestion of chewable CBD gummies will help to present calmness and comforting to the physique. It possibly helps to fight agonizing ailments, inflammatory illnesses, burning sensations, soreness, muscle mass stiffness, and irritation in distinct regions of the physique. 

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    CBD gummies have anti-anxiousness, and antidepressant houses that support to battle psychological wellbeing ailments as properly as supply a strain-totally free thoughts. These gummies command pressure hormones and assist reduced stress degrees. 

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  • Osteoporosis Medications: Benefits vs. Side Effects

    Osteoporosis Medications: Benefits vs. Side Effects

    There are many medication options to treat osteoporosis, a disease that weakens bones and makes them brittle and prone to breaking. When choosing the right medicine, several factors must be considered, including menopausal status, disease severity, and the drug’s cost, risks, and delivery method—injection, oral, or intravenous (IV) infusion.

    This article reviews the factors that go into choosing an osteoporosis drug. A list of osteoporosis medications, including their mode of action and side effects, is also provided.

    IndiaPix/IndiaPicture / Getty Images


    Osteoporosis Medications: Deciding Factors

    Osteoporosis causes no symptoms, including pain (unless a fracture is present). Despite being a “silent” disease, medication may be necessary to reduce your fracture risk. Fractures can be devastating and are associated with a poor quality of life.

    As you discuss osteoporosis treatment with your healthcare provider, the following factors will be taken into account.

    Terminology

    Verywell Health prefers to use inclusive terminology. But when citing health authorities or research, the terms for gender and sex from those sources are used. Food and Drug Administration (FDA) guidelines for drug indications often use binary gender terms.

    In this article, “female” refers to people assigned female at birth, and “male” refers to people assigned male at birth. Talk to a healthcare provider to determine whether screening or a medication is indicated for you.

    Menopause, Gender, and Age

    Postmenopausal females are at high risk for developing osteoporosis and bone fractures because they have low estrogen levels.

    In addition to menopause and declining estrogen levels, bones naturally weaken and thin with advancing age. As such, medication may be advised to treat postmenopausal females and males aged 50 years or older with osteoporosis.

    Overall, patient sex and age both influence the choice of therapy. This is because some osteoporosis drugs are FDA-approved for both older males and postmenopausal females. Other osteoporosis medications are only approved for postmenopausal females. Likewise, some osteoporosis medications are better for younger postmenopausal females and others for older ones.

    Extent of Bone Loss

    The extent of your bone loss is reflected in your T score.

    The T score is a number that compares your bone’s quality with that of an average young person with healthy bones. Individuals with normal bone density have a T score between plus 1 and minus 1, whereas individuals with osteoporosis have a T score of minus 2.5 or less. 

    Since osteoporosis medications work in distinct ways and have varying levels of effectiveness, the severity of your osteoporosis impacts your choice of therapy.

    Side Effects and Personal Preferences

    Osteoporosis medications have unique side effect profiles and contraindications (reasons not to take the drug). You may not be able to tolerate certain drugs, or they may be unsafe for you to take.

    Moreover, osteoporosis medications differ in their delivery method and dosing schedules. You may prefer, for example, a pill vs. a shot or a monthly vs. daily medication.

    Cost and Insurance Coverage

    Insurance companies usually cover osteoporosis medication, but how much depends on your insurance type and co-pay. If you have Medicare, the cost of prescription drugs can be lowered through a benefit called Medicare Part D.

    If you are considering an osteoporosis medication, check the medication or your insurance company’s website to find out if it’s covered. Your healthcare provider can also refer you to a social worker or billing specialist for assistance.

    Length of Time on Medication and Monitoring

    When taking an osteoporosis medication, your healthcare provider will monitor you periodically to see how well it works and evaluate for any adverse reactions.

    Some individuals may need to change their drug, perhaps because they continue to lose bone or develop an intolerable side effect. Also, some medications can only be used for a certain length of time due to safety concerns or reduced benefits with long-term use.

    The degree of monitoring required and the time you can take a drug can ultimately affect your choice.

    List of Osteoporosis Medications

    Osteoporosis medications work to prevent fractures by either slowing bone loss or forming new bone; however they cannot fully reverse the condition.

    Here is a list of osteoporosis medications, including their mode of action and how they are taken. A summary chart that includes the drugs’ common and serious side effects is also provided.

    Bisphosphonates

    Bisphosphonates are the most commonly used drugs to treat osteoporosis.

    They are used to treat males and postmenopausal females with osteoporosis and steroid-induced osteoporosis (bone weakening caused by chronic steroid use, for example, prednisone).

    Bisphosphonates work by slowing the natural breakdown of bone. Several types are available, varying in their dosing and delivery method (pill, liquid, or IV infusion).

    Options include:

    • Binosto, Fosamax (alendronate): This pill is taken once daily or weekly.
    • Actonel, Atelbia (risedronate): This pill is taken once daily, weekly, or monthly.
    • Boniva (ibandronate): This pill is taken once daily or monthly or as an injection every three months.
    • Reclast (zoledronic acid): This IV infusion (through the vein) is given once a year.

    For oral bisphosphonates, the pill must be taken in the morning on an empty stomach with 4 ounces (half a cup) of water. You then need to sit or stand upright for 30 minutes before eating. The purpose is to avoid irritating the esophagus (the tube that carries food from your mouth to your stomach.

    Individuals who cannot follow these instructions or those with esophageal disorders should not take an oral bisphosphonate.

    Bisphosphonates are generally taken for three to five years. Taking one for seven years or more may rarely increase the risk of an unusual bone break in the thigh bone (atypical femur fracture).  

    Also, some people worry about developing a complication called osteonecrosis (death of a portion of bone) of the jaw with bisphosphonates. This risk is minimal and more common in individuals taking a bisphosphonate as part of their cancer treatment, not for osteoporosis.

    Prolia (Denosumab)

    Prolia (denosumab) is used in postmenopausal females at high risk for fracture or who have not responded to or tolerated other osteoporosis drugs.

    High risk for fracture is generally defined as someone with a history of osteoporotic fracture or multiple risk factors for fracture,

    Prolia is injected underneath the skin, usually by a healthcare provider, once every six months. It works by blocking a protein involved in the formation of cells that break bone down (osteoclasts).

    Prolia can cause or worsen low calcium levels in the blood (hypocalcemia), so this abnormality must be corrected before starting Prolia (if present).

    In addition, stopping Prolia is associated with rapid bone loss. As a result, a drug holiday (taking time off from using the drug) is not advised for people taking Prolia. If the drug needs to be stopped, a bisphosphonate is usually prescribed to preserve bone density.

    Evista (Raloxifene)

    Evista (raloxifene) is a type of drug called a selective estrogen receptor modulator (SERM).

    What Is a SERM?

    A SERM is an estrogen-like medication that mimics estrogen in some parts of the body and blocks the effects of estrogen in other parts. 

    Evista can slow down bone loss in postmenopausal females and is taken as a pill once a day.

    Evista increases the risk of death due to stroke in postmenopausal females with (or those at risk for) stroke. It also increases the risk of blood clots in your legs (deep vein thrombosis). lungs (pulmonary embolism), and eyes. As such, females at risk for stroke or blood clots should not take this medication.

    Parathyroid Hormone/Parathyroid Hormone-Related Protein

    Forteo (teriparatide) or Tymlos (abaloparatide) are approved for postmenopausal females at high risk for fracture.

    Forteo is also FDA-approved for males at high risk for fractures and for treating osteoporosis in people of any sex associated with long-term steroid therapy (taking 5 milligrams or more of prednisone daily).

    Forteo and Tymlos work by stimulating bone formation. They are given as daily injections underneath the skin and are available in prefilled syringe pens so people can administer the shots themselves at home.

    Forteo and Tymlos are used for up to two years. This restriction is due to the possible risk of developing osteosarcoma (a type of bone cancer). Keep in mind, though, osteosarcoma has only been seen in studies of animals, not humans.

    Evenity (Romosozumab)

    Evenity (romosozumab) may treat postmenopausal females at a high risk of fractures. A healthcare provider gives Evenity as a monthly injection underneath the skin.

    Evenity enhances bone formation by blocking sclerostin, a protein that stops building new bone. The drug can only be used for up to one year because it becomes less effective at reforming bone.

    Also, Evenity may increase the risk of heart attack and stroke, although it’s unclear why. Until more is known, the drug should not be given to people with a history of or an increased risk of heart attack or stroke.

    Summary of Osteoporosis Medications
      Delivery Dosing Common Side Effects Serious Side Effects
    Oral or Injected Bisphosphonate (e.g., Fosamax, Actonel, Boniva) Pill or injection Daily, weekly, monthly, or every three months (injection) Back pain, joint/arm/leg pain, nausea, heartburn, stomach pain, Severe esophageal inflammation, severe muscle/joint/bone pain, low blood calcium levels, jaw osteonecrosis, atypical femoral fracture
    Reclast (zoledronic acid) Infusion Yearly Fever, muscle/joint aches, headache, arm/leg pain Low blood calcium levels, jaw osteonecrosis, atypical femoral fracture, severe muscle/joint/bone pain
    Prolia (denosumab) Injection Every 6 months Back pain, arm/leg pain, muscle/joint pain, high cholesterol, bladder infection Low blood calcium levels, jaw osteonecrosis, atypical femur fractures, serious infections
    Evista (raloxifene) Pill Daily Hot flashes, leg cramps, leg swelling, flu-like symptoms, joint stiffness, sweating Increased risk for blood clots and death due to stroke in patients with (or at risk for) stroke
    Forteo (teriparatide) Injection Daily Joint stiffness, pain, nausea, high calcium levels Osteosarcoma (in animal studies)
    Tymlos (abaloparatide) Injection Daily Calcium in the urine, dizziness, nausea, headache, palpitations, unusual tiredness, stomach pain Osteosarcoma (in animal studies)
    Evenity (romosozumab) Injection Monthly Joint stiffness, headache Low blood calcium levels, jaw osteonecrosis, atypical femur fractures, may increase risk of heart attack and stroke
    Source

    Medication Alternatives

    There is limited scientific evidence supporting the benefits of alternative treatments for osteoporosis, including taking traditional Chinese medicine herbs or engaging in practices like yoga and acupuncture.

    That said, these therapies may be reasonable to incorporate into your osteoporosis treatment plan, mainly if they help you feel better. Before starting any new treatment, always discuss it first with a healthcare provider. You want to be sure the therapy is safe and proper for your care.

    An Integrative Approach to Osteoporosis Treatment

    Osteoporosis cannot be fully cured or reversed, but there are things you can do to slow bone loss and help rebuild bone tissue.

    Take an integrative approach, which includes healthy lifestyle behaviors and, sometimes, medication.

    Healthy lifestyle behaviors include:  

    • Eat a well-balanced diet plentiful in fruit and vegetables that include calcium, vitamin D, and protein. Supplements, especially vitamin D, may be needed.
    • Participate in regular exercise. Include weight-bearing exercises (e.g., walking or playing tennis) and resistance exercises (e.g., lifting weights).
    • Avoid secondhand smoke, and quit smoking if you do.
    • Drink alcohol in moderation, which means no more than one drink a day for females and no more than two daily drinks for males.
    • Engage in fall-prevention strategies (e.g., declutter, remove rugs, improve room lighting, wear supportive shoes).

    Summary

    Osteoporosis is associated with bone thinning and weakening, which makes bones prone to breaking. Treatment with medication is sometimes recommended to prevent bone breaks.

    Several drugs are available, including bisphosphonates, estrogen-like medications, and parathyroid hormone. These drugs vary in their modes of action, delivery method, dosing schedule, and side effects. Such factors must be carefully considered when making the decision about the right therapy for you.

    Frequently Asked Questions

    • Can you treat osteoporosis without medication?

      Healthy lifestyle habits, such as regular exercise and eating a well-balanced diet, are essential for strengthening your bones. However, for some individuals with osteoporosis, medication may be advised to augment this effect and further protect against fractures.

    • What is the newest osteoporosis medication?

      The osteoporosis medication Evenity (romosozumab) was FDA-approved in 2019 to treat osteoporosis in postmenopausal females at high risk of breaking a bone.

    • Which osteoporosis medication is the safest?

      Osteoporosis drugs have different risks and side effects profiles. Generally speaking, a bisphosphonate, like Fosamax or Actonel, is the first choice when choosing a medication for osteoporosis.

    Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.

    1. Gold T, Williams SA, Weiss RJ, et al. Impact of fractures on quality of life in patients with osteoporosis: a US cross-sectional survey. J Drug Assess. 2019;8(1):175-183. doi:10.1080/21556660.2019.1677674

    2. LeBoff MS, Greenspan SL, Insogna KL, et al. The clinician’s guide to prevention and treatment of osteoporosis. Osteoporos Int. 2022;33(10):2049-2102. doi:10.1007/s00198-021-05900-y

    3. Ji MX, Yu Q. Primary osteoporosis in postmenopausal women. Chronic Dis Transl Med. 2015;1(1):9-13. doi:10.1016/j.cdtm.2015.02.006

    4. Sözen T, Özışık L, Başaran NÇ. An overview and management of osteoporosis. Eur J Rheumatol. 2017;4(1):46-56. doi:10.5152/eurjrheum.2016.048

    5. Adler RA, El-Hajj Fuleihan G, Bauer DC, et al. Managing osteoporosis in patients on long-term bisphosphonate treatment: report of a task force of the American Society for Bone and Mineral Research. J Bone Miner Res. 2016;31(1):16-35. doi:10.1002/jbmr.2708

    6. Cummings SR, Ferrari S, Eastell R, et al. Vertebral fractures after discontinuation of denosumab: a post hoc analysis of the randomized placebo-controlled FREEDOM trial and its extension. J Bone Miner Res. 2018;33(2):190-198. doi:10.1002/jbmr.3337

    7. Food and Drug Administration. Evista labeling.

    8. Food and Drug Administration. Highlights of prescribing information: Forteo (teriparatide injection).

    9. Saag KG, Petersen J, Brandi ML, et al. Romosozumab or alendronate for fracture prevention in women with osteoporosis. N Engl J Med. 2017;377(15):1417-1427. doi:10.1056/NEJMoa1708322

    10. Hejazi ZA, Namjooyan F, Khanifar M. Complementary and alternative medicine for osteoporosis. Iran J Med Sci. 2016;41(3 Suppl):S27.

    11. National Institutes of Health Osteoporosis and Related Bone Diseases National Resource Center: Osteoporosis overview.

    12. Food and Drug Administration. FDA approves new treatment for osteoporosis in postmenopausal women at high risk of fracture.


    By Colleen Doherty, MD

     Colleen Doherty, MD, is a board-certified internist living with multiple sclerosis.

  • Proper CBD Gummies Shark Tank [REVIEWS] MUST WATCH SIDE EFFECTS FIRST?

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  • CBD Doesn’t Reduce THC Effects, Cannabis Study Finds

    CBD Doesn’t Reduce THC Effects, Cannabis Study Finds

    The scientific discussion on whether CBD impairs the outcomes of THC on the human human body is nevertheless open up. Even so, the authors of a new hashish analyze observed that CBD won’t reduce the effects of THC.

    The results of a review released in the Journal of Neuropsychopharmacology exhibit that CBD has no impairing outcomes on THC, in contrast to other studies on the matter.

    Scientists of the King’s University of London have conducted a analyze to uncover whether or not the conversation of CBD with THC may perhaps reduce the effects of the latter.

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    The authors of this analyze have conducted a scientific trial on 46 volunteers between 21 and 50 many years outdated who experienced utilised hashish at the very least once in the previous but experienced not employed hashish for a lot more than 1 week around the past 12 months.

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    Quite a few elements may well add to the intoxicating consequences of THC, like the methods of consuming cannabis, and we have to maintain in head that the effects of CBD and THC may perhaps differ from human being to man or woman.