Discover the future of the growing Cannabidiol (CBD) Oil Market and Cannabidiol Market with our latest research report. With a projected market size of over $6.77 billion & $25.15 billion, join the booming market and explore its potential.
As per the recent market research report published by Extrapolate, the global Cannabidiol (CBD) Oil Market to generate a revenue of over USD 6.77 billion by 2032 from USD 580 million in 2022 at a CAGR of 31.2{fe463f59fb70c5c01486843be1d66c13e664ed3ae921464fa884afebcc0ffe6c} from 2023 to 2032.
As the demand for CBD products rises, the Cannabidiol (CBD) Oil Market is expected to expand rapidly over the next few years. This rapid growth is largely driven by the increasing awareness and acceptance of CBD oil, as well as changing consumer preferences and attitudes toward CBD products. The rising popularity of CBD oil is due to a number of factors, including its potential health benefits. As per Extrapolate, it has been witnessed that CBD oil may further help reduce inflammation, alleviate pain, reduce anxiety and depression, and even help fight cancer. Additionally, CBD oil has been utilized to treat a variety of skin conditions, including acne and eczema.
The market is further fueled by the growing number of CBD-infused products available. From tinctures, capsules, and gummies to lotions, oils, and even pet products—there is a dizzying array of options when it comes to CBD-related products. Furthermore, new and innovative products are constantly being released. In addition to the obvious medical applications, the CBD oil market is also benefitting from the trend of people looking for natural alternatives to traditional medications. Many consumers find CBD oil to be a more palatable option than pharmaceuticals, and this has driven the growth of the industry even further.
The global Cannabidiol (CBD) Oil market is segment as follows:
Segmentation By Type
Segmentation By End-Use
Pharmaceutical Companies to Remain the Largest End-Users in the Cannabidiol (CBD) Oil Market
The current market for CBD oil is primarily dominated by pharmaceutical companies, which account for the majority of sales. Pharmaceutical companies are attracted to the industry due to its low cost of entry, high margins, and potential for growth. Moreover, they have added advantage over other players in the market due to their extensive experience with manufacturing and distributing drugs. This expertise gives them a greater degree of control over production costs, which they can then pass on to consumers with competitive pricing.
The demand for CBD oil is expected to increase over the next few years, driven by the increasing acceptance of CBD as a potential treatment for a number of medical conditions.
B2B Distribution to Continue Holding Its Dominance over Global Cannabidiol (CBD) Oil Market
In terms of B2B distribution, there is strong demand for CBD oil from major buyers such as distributors, retailers, and medical professionals. It allows for bulk purchasing and wholesale pricing, creating long-term partnerships, and providing access to a wider range of products. Additionally, B2B helps ensure product quality and safety by allowing businesses to access information about the source and production process.
Wherein, distributors play an important role in ensuring that products reach the end consumer in a timely and efficient manner. Retailers provide CBD products to consumers through brick-and-mortar stores and online platforms. Medical professionals are utilizing CBD for therapeutic purposes, which is driving the demand for these products. In addition, businesses in the hospitality industry are rapidly using CBD-infused products for their calming and relaxing effects.
Furthermore, the production of CBD-infused products is increasing as manufacturers take advantage of the growing demand for these products. Companies have started to invest in research and development, as well as marketing, to gain a competitive edge in the cannabidiol oil market. Additionally, there is strong demand for CBD oil from countries such as Canada, the US, and Australia, where the legal status of CBD is more favorable.
The presence of several large players in the region is also contributing to the growth of the CBD oil industry. Major companies such as Cannoid, LLC, Endoca, and Elixinol are investing heavily in research and development, as well as marketing and production capabilities, in order to capitalize on the growing demand for CBD products.
North America to Remain the Largest Consumer and Revenue Generating Region
North America is expected to remain the largest consumer and revenue-generating region in the global CBD oil market over the forecast period. It is gaining momentum in the region due to the increasing awareness about the therapeutic and medicinal benefits of cannabidiol (CBD). The growing acceptance of CBD as an alternative form of relief from chronic conditions such as anxiety, pain, seizures, and insomnia is driving demand for these products, especially in the US. Furthermore, the increasing popularity of CBD-infused cosmetics and beauty products is also driving the market forward. As more people become aware of the potential health benefits of CBD, the demand is only expected to increase further in the North American CBD Oil Market.
Apart from this, countries such as Canada, Mexico, and Colombia are rapidly legalizing the use of medical marijuana, which is further boosting the market in the region. Some countries even allow CBD products to be sold in pharmacies and other retail outlets. These changes are driving consumer demand, especially among individuals looking for natural alternatives in place of traditional medications.
Major Points from TOC:
Chapter 1. Executive Summary Chapter 2. Research Methodology Chapter 3. Market Outlook Chapter 4. COVID-19 Impact on Cannabidiol (CBD) Oil Market Chapter 5. Global Cannabidiol (CBD) Oil Market Overview, By Type, 2018 – 2032 (USD Million) Chapter 6. Global Cannabidiol (CBD) Oil Market Overview, By End-Use, 2018 – 2032 (USD Million) Chapter 7. Global Cannabidiol (CBD) Oil Market Overview, By Distribution Channel, 2018 – 2032 (USD Million) Chapter 8. Global Cannabidiol (CBD) Oil Market Overview, By Geography, 2018 – 2032 (USD Million)
Chapter 9. North America Cannabidiol (CBD) Oil Market Overview, By Countries, 2018 – 2032 (USD Million)
Part II: Cannabidiol (CBD) Market Outlook To 2032:
The Cannabidiol (CBD) Industry has been experiencing tremendous growth in recent times. According to a recent market research analysis by Extrapolate, the global Cannabidiol (CBD) Market was valued at USD 6.06 billion in 2022 and is expected to reach a valuation of USD 25.15 billion by 2032 at a CAGR of 15.3{fe463f59fb70c5c01486843be1d66c13e664ed3ae921464fa884afebcc0ffe6c} during the forecast period.
In 2018, the United States incorporated The Farm Bill to legalize CBD, hemp and its other derivatives. This has led to an increase in demand for CBD products. As per Extrapolate’s recent study, the global CBD market valuation has expanded by 60{fe463f59fb70c5c01486843be1d66c13e664ed3ae921464fa884afebcc0ffe6c} since the declaration of the 2018 Farm Bill. In addition, numerous studies have confirmed that CBD has medical potential for treating various conditions like chronic pain, inflammation, anxiety, depression, epilepsy, and more.
CBD’s drug delivery system has improved over time to make it more bioavailable, providing consumers a consistent and dependable dosage. The global CBD market is expected to grow significantly in the coming years due to increased demand and the entry of new market players. This growth will also be driven by supportive regulations, investment in research and development, and the launch of new products.
CBD’s popularity has skyrocketed in recent years because of its therapeutic properties and medicinal benefits. As a non-psychoactive compound, it does not produce the intoxicating effects of marijuana, making it a safer and more appealing option for people seeking relief from various ailments. The key factors driving demand for CBD include its perceived medical benefits and the updated legal status. With its increasing availability, more people are choosing it as a natural remedy over traditional pharmaceuticals, and its legal status has become more accepted in many countries and states.
Competitive Landscape:
The global cannabidiol market is highly fragmented, with prominent players such as CannaVEST, Kazmira, CW Hemp/CW Botanicals, Freedom Leaf, Endoca, and Medical Marijuana, Inc., among others. These companies are engaged in offering a wide range of CBD-based products in various forms, such as oils, topicals, edibles, tinctures, capsules, and beverages. Furthermore, these companies are focusing on expanding their product portfolios by introducing new product offerings.
Online Sales of CBD Products is Gaining Momentum in North America and Europe
Online sales of cannabidiol (CBD) products have seen a strong momentum of growth in North America and Europe. This is mainly due to the increasing awareness and acceptance of CBD products in these regions and the relaxation of certain regulations preventing its use. In North America, the United States captured the largest market for CBD products, accounting for over 70{fe463f59fb70c5c01486843be1d66c13e664ed3ae921464fa884afebcc0ffe6c} of the total market share. The increasing demand for CBD products, coupled with the growing acceptance among consumers, has contributed to the growth of online sales of CBD products in the US.
Meanwhile, Canada is also emerging as a lucrative market for CBD products, with sales of legal CBD products estimated to reach USD 560 million by 2028.
In Europe, the UK is one of the leading markets for CBD products. According to The Centre for Medical Cannabis, the Europe CBD market size was valued at 2.53 billion in 2021. This is mainly due to the relaxed regulations regarding the use of CBD products in the UK, as well as the increasing awareness of the health benefits offered by CBD products. Meanwhile, Germany and Switzerland are two of Europe’s leading markets for CBD products.
The global Cannabidiol (CBD) Market is segmented as follows:
Segmentation (by Type)
Hemp-derived Type
Marijuana-derived Type
Marijuana Segment Captured Over 50{fe463f59fb70c5c01486843be1d66c13e664ed3ae921464fa884afebcc0ffe6c} Revenue of the Global Cannabidiol Market
The global cannabidiol (CBD) market has witnessed significant revenue growth in the past few years. In 2022, the marijuana segment captured over 50{fe463f59fb70c5c01486843be1d66c13e664ed3ae921464fa884afebcc0ffe6c} of the total market revenue, driven by increasing demand for cannabis-based products and the expansion of online retail channels worldwide. This is due to the rising awareness among consumers of the therapeutic potential of CBD-derived products, which has led to an increase in product demand. Additionally, rapid legislative changes in the United States and other countries have made hemp-derived CBD legal, and this has created further opportunities for the industry.
In the United States, marijuana has been federally legalized for medical and recreational use. This has created a conducive regulatory environment for the sale, manufacture, and distribution of cannabis products in the country.
Going forward, the introduction of new technological innovations and the proliferation of digital marketing strategies are expected to further drive the marijuana segment’s market potential. The emergence of new forms of marijuana consumption, such as edibles, beverages, and vape pens, is likely to open up a range of opportunities for the industry. Moreover, ongoing efforts by companies to create a more open cannabis trade will lead to further growth in the coming years.
Key Points From TOC: 1 Research Methodology and Statistical Scope 2 Cannabidiol (CBD) Market Overview 3 Cannabidiol (CBD) Market Competitive Landscape 4 Cannabidiol (CBD) Industry Chain Analysis 5 The Development and Dynamics of Cannabidiol (CBD) Market 6 Cannabidiol (CBD) Market Segmentation by Type 7 Cannabidiol (CBD) Market Segmentation by Application 8 Cannabidiol (CBD) Market Segmentation by Region 9 Key Companies Profiled 10 Cannabidiol (CBD) Market Forecast by Region 11 Forecast Market by Type and by Application (2023-2032) 12 Conclusion and Key Findings
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With so numerous articles in the archives and more than a ten years of crafting to refer to, it’s intriguing to seem back again at how the contributors to this site have examined rising healthcare problems. Above the same period of time of this blog’s lifetime, the availability of marijuana for health-related use has expanded drastically, paving the way for eventual legalization. Even incredibly early on, this website was careful about the buzz about its clinical opportunity. The earliest publish I can discover was from 2009, when Peter Lipson wrote about its emerging use. He mentioned:
As marijuana turns into more and more available for health care use, practitioners of science-based medication need to have to evaluate the proof for the use of this drug. In analyzing a new drug, we will have to question a range of thoughts, such as all those of security, efficacy, and probably redundancy. Statements for the efficacy of marijuana have a tendency to be hyperbolic, with no condition remaining exempt from its rewards.
In 2014, David Gorski wrote a collection of posts on medical marijuana, likening it to “the new herbalism” and noting:
It is not enough just to say hashish (or whatever cannabinoid drug or by-product you could possibly desire to use) is “efficacious” versus this disease or this condition. We have to have to know how efficacious it is in comparison to the present common of treatment.
The general public enthusiasm for the recreational and medical use of marijuana is very clear. Use has developed radically in spite of constrained proof. Now we have a research that can help to even more clarify its potential position as a drugs. In a new paper released in the Journal of Scientific Oncology, researchers researched if cannabidiol (CBD) improved symptom control in patients with highly developed cancer.
Cannabidiol (CBD) oil is a person of the quite a few chemical compounds referred to as cannabinoids that are isolated from hashish. Hashish incorporates more than 400 chemical compounds like at minimum 120 cannabinoids, which stimulate cannabinoid receptors in the physique. (Sure, we have cannabinoid receptors and we even make our have cannabinoids.) The most nicely-examined cannabinoids in the analysis setting are delta-9-tetrahydrocannabinol (THC) and CBD. CBD does not have the psychoactive profile of THC, and though it has been the resource of sizeable medical interest, its primary established part as a healthcare merchandise is for the treatment of types of childhood epilepsy.
Cannabidiol is a plausible and even promising procedure for the indications of superior cancer. Patients with innovative levels of most cancers can experience exhaustion, anorexia and other distressing indicators. Hashish has been promoted as a much more “natural” procedure alternative, so this examine was designed to assess if CBD oil, in combination with standard pallative care, minimized patient symptom load.
The trial
The analyze, titled “Phase IIb Randomized, Placebo-Controlled, Dose-Escalating, Double-Blind Review of Cannabidiol Oil for the Aid of Signs in Sophisticated Most cancers (MedCan1-CBD)”, was a randomized, placebo-managed study of CBD that took location in 5 professional medical centres in Queensland, Australia. Participants experienced advanced (palliative) cancer, and have been around the age of 18 with signs or symptoms resulting in distress (as measured by a standardized scoring software), experienced no THC in their urine, and experienced satisfactory mobility (effectiveness status) and cognitive operate.
All patients in the research were to acquire typical palliative treatment treatment. Sufferers had been randomized to acquire CBD oil (100mg/mL) or a matched placebo. Doses ended up increased gradually each individual 3rd working day, as they could tolerate, around 14 times, starting at 50mg once every day up to a most of 200mg 3 times each day. Individuals ended up presented the choice of keeping on the ideal dose for two further months.
Sufferers ended up assessed by phone employing a standardized instrument (evaluating agony, fatigue, nausea, sleepiness, shortness of breath, urge for food, anxiousness, melancholy and over-all properly-currently being) every single 3-4 times, with deal with-to-face assessments at days 14 and 28. This rating, at working day 14 compared to working day zero, was the key end result measure. Secondary actions integrated specific symptom scores, discomfort control (as calculated by oral morphine equivalents), and adverse gatherings.
Outcomes
Of 215 clients invited to participate, in the end 144 individuals have been randomly assigned in excess of a 33-month time period. Two individuals had been eventually eradicated top to 58 contributors on CBD and 63 on the equivalent placebo. The teams were comparable in phrases of how a lot of people remained in the review at working day 14 and working day 28. Affected individual properties had been equivalent with the exception of the placebo team possessing a even worse baseline symptom rating at randomization.
Overall symptom burden: Indicators enhanced in both of those groups with no important variations between the two group. (Indicators essentially improved more in the placebo team, but not drastically). Modified for the distinction in the baseline rating, there was fundamentally zero variance involving the two groups at working day 14. There was also no variance in the proportion of “responders”, outlined as a decrease in the symptom scale of 6 or much more:
Proportion of responders (tumble in Whole Symptom Distress Rating (TSDS) ≥ 6 amongst baseline and working day 14) in each individual arm (placebo: 37 of 63 [58.7{fe463f59fb70c5c01486843be1d66c13e664ed3ae921464fa884afebcc0ffe6c}] CBD: 26 of 58 [44.8{fe463f59fb70c5c01486843be1d66c13e664ed3ae921464fa884afebcc0ffe6c}], P = .13)
Transform in particular person symptoms: All steps in the symptom scale enhanced (fell) around time in both teams. There was no variance concerning teams in phrases of actual physical, emotional, or properly-getting, or in any unique element (e.g., ache, nausea, hunger):
Participant-chosen dose: The median closing dose selected by individuals was 6mL/working day in the placebo team and 4mL/day in the CBD group (equivalent to a dose of 400mg/working day).
Soreness regulate: There was no variation detected concerning arms in terms of oral morphine equivalents utilised, or the alterations in use over the duration of the examine.
Other medications: There was no correlation in between the participant-picked dose of CBD/placebo and opioid dose, or the use of prescription drugs like benziodiazepines and antipsychotics.
International impressions of transform: Most participants reported sensation far better or a great deal far better at working day 14 and 28, frequently even with no change in the symptom rating. There were being no distinctions involving the groups.
Adverse outcomes: There ended up no discrepancies in occasions of particular curiosity among the groups at days 14 and 28 in terms of adverse functions, with a nonsignificant raise in somnolence and belly agony and a trend of much more vomiting in the placebo group. In conditions of other adverse gatherings, there was a significant raise in shortness of breath reported in the CBD team. There ended up no dissimilarities in hospitalizations (none connected to the research drug) or in in general survival.
Conclusion
When there has been major enthusiasm in the use of cannabis as a health care treatment method, this randomized controlled trial of CBD oil in individuals located no benefit about conventional care. Inspite of a plausible mechanism of motion, CBD did not increase stress and anxiety, melancholy, or any person symptom substantially. CBD oil was perfectly tolerated and there were being several aspect results with the probable larger price of somnolence similar to CBD use. This trial differs from other analysis in that it was very well-built to reduce bias, used a standardized, verified CBD products, and was powered to detect if CBD available any meaningful rewards. It calculated effects using a validated scale that captures significant affected individual signs. The authors conclude:
This research has substantial implications for policymakers concerning the two authorised indications for MC and its harmless use. Professional medical cannabis has been authorised in many nations for palliative care in the perception that it may possibly improve the [quality of life] of people with superior disease. CBD is a common hashish products in the neighborhood as it has no psychoactive outcomes and does not impair driving ability. With recent proof, it is tricky to justify governing administration subsidization of the price tag of CBD nor suggest that sufferers pay out for CBD products and solutions.
When no solitary study is definitive, this trial indicates that CBD, inspite of its recognition, could not give any advantage to people handling the symptoms of highly developed cancer in a palliative location.
Scott Gavura, BScPhm, MBA, RPh is dedicated to enhancing the way drugs are used, and examining the occupation of pharmacy through the lens of science-primarily based medication. He has a expert fascination is increasing the value-powerful use of medicine at the inhabitants stage. Scott retains a Bachelor of Science in Pharmacy degree, and a Master of Enterprise Administration degree from the College of Toronto, and has concluded a Accredited Canadian Healthcare facility Pharmacy Residency Software. His skilled background contains pharmacy function in both of those group and healthcare facility options. He is a registered pharmacist in Ontario, Canada.

Scott has no conflicts of desire to disclose.

Disclaimer: All sights expressed by Scott are his private sights on your own, and do not symbolize the opinions of any existing or previous businesses, or any companies that he may well be affiliated with. All details is supplied for discussion uses only, and ought to not be used as a substitution for session with a licensed and accredited wellbeing skilled.
Disclaimer: This is sponsored content. All opinions and views are of the advertiser and do not reflect the same of WFTS.
If you often experience symptoms of excessive and irrational fear, worry, and apprehension, there are steps you can take to feel better. Natural therapies such as CBD-based wellness products can often alleviate anxiety symptoms.
We review the best CBD oils for anxiety to help you find one that suits you. We’ll also discuss choosing the best CBD oil and exploring the research behind using CBD for anxiety.
Best CBD Oil for Anxiety
Anxiety disorders are becoming more prevalent due to stress from work, health concerns, and financial commitments. Studies show that CBD oil may help treat anxiety and alleviate depression by altering serotonin levels in the brain [1]. Here are our top choices.
Start with organic farming practices, and you’ll get the highest-quality hemp—that’s the philosophy behind Cornbread Hemp, a firm founded on Kentucky’s 250-year hemp legacy.
Cornbread Hemp’s products are USDA-certified organic and manufactured with hemp flowers only—no stems, stalks, leaves, or seeds. Once the flowers are separated from the stalks, they undergo organic sugarcane ethanol extraction, with no further processing, keeping all the hemp goodness in the formula.
Cornbread Hemp’s website has third-party certificates of analysis (COAs) from ISO 17025-certified labs. If you wish to get results for a specific product, you can search by batch number or study the COAs for all items before making a purchase.
Pros
Organic whole flower formula.
Full-spectrum CBD oil.
Subjected to third-party laboratory testing.
Products are backed by a 30-day guarantee.
Discounts of up to 50{fe463f59fb70c5c01486843be1d66c13e664ed3ae921464fa884afebcc0ffe6c} for veterans and those with long-term disabilities.
Cons
The pricing is higher than that of other quality CBD products.
Who Is Cornbread Hemp Best For?
Cornbread Hemp’s Full Spectrum CBD Oil is beneficial for everyday stress alleviation, muscle and joint relaxation, a functioning sleep schedule, and overall well-being.
With Whole Flower (25mg of CBD to 1mg of THC) and Distilled (50mg of CBD to 1mg of THC) extracts, you can use the Whole Flower extract for improved sleep and the Distilled extract to stay calm, yet alert throughout the day.
Who Should Avoid Cornbread Hemp?
If you’re pregnant, nursing, or have serious medical conditions, consult your primary care physician before using this product.
Potential Side Effects
THC can cause excessive sleepiness if you’re particularly sensitive and increase your appetite.
There’s a risk that you may test positive for cannabis with any THC-containing product.
Summary
Cornbread Hemp is a high-quality CBD oil that uses only hemp flowers to maximize its therapeutic effects. However, consult your healthcare provider to see whether Cornbread Hemp can help you control your anxiety.
Spruce is best for you if you need immediate relaxation. With the specifications of 750mg and 2,400mg in potency, anxiety sufferers report that the oil is effective, helps deliver the strongest relief possible, and improves their sleep.
Research also shows that full-spectrum organic hemp CBD oils, such as Spruce, are beneficial in treating pain and inflammatory diseases [2]. This means that each dropper of Spruce has multiple therapeutic properties that can provide immediate and long-term pain relief—essential for those suffering from chronic pain.
Who Should Avoid Spruce?
It is best to avoid all THC consumption, Spruce included, if you regularly undergo drug testing or are pregnant.
Potential Side Effects
THC can cause excessive sleepiness, which may have an additive effect when mixed with other sedatives you’re taking, as well as an increased appetite.
Summary
Spruce offers pure CBD oil products tested by a third-party lab. Customers may view the lab findings for the company’s CBD products online, ensuring they purchase a pure, third-party-tested product. In addition, their products are pesticide-free and don’t include heavy metals or biotoxins.
Cornbread Hemp’s gluten- and GMO-free hemp seed oil is ideal if your dog is stressed from thunderstorms, fireworks, socializing with other dogs or humans, visiting the vet, or traveling.
Who Should Avoid Pet?
Pet CBD oil should not be used if your dog has been diagnosed with low blood pressure or hypotension. If your pet has been diagnosed with hypotension or it has been a while since their last blood pressure check, make an appointment with your veterinarian.
Potential Side Effects
As CBD can have sedative effects, your dog may sleep more often after you give them Pet oils.
Summary
Cornbread Hemp’s Pet CBD oil is proud of its all-natural, well-formulated solutions and cutting-edge technologies. The brand produces its oils using only the finest all-organic hemp grown in Colorado and does frequent internal and external lab evaluations to ensure the quality.
If you have trouble sleeping, NuLeaf Naturals could be the CBD oil for you.
As a whole-plant extract, this high-quality CBD oil contains the complete spectrum of cannabinoids and terpenes, making it a helpful remedy for sound sleep.
Research shows different terpenes have natural calming and hypnotic properties [3]. Additionally, the oil may help to alleviate brain stress by enhancing memory and reducing brain fog.
Who Should Avoid NuLeaf Naturals?
Some drugs, such as blood thinners, may interfere with the CBD in NuLeaf. Consequently, it’s critical to see your doctor before taking this supplement.
Potential Side Effects
CBD and some terpenes have sedative effects, so caution is advised if you take sedatives or need to increase or maintain your energy levels.
Summary
NuLeaf Naturals’ pure CBD oil products contain all-natural, organic, and non-toxic components. The oil has all of the necessary elements to promote brain and body relaxation and tranquility.
With its innovative thermal extraction technology, which aims to optimize terpene content, Vital Plan Select can help alleviate the frequently agonizing symptoms that migraine sufferers experience.
A 2018 study found that cannabinoids and other constituents like terpenes—the natural compounds in the cannabis plant’s flower or bud—have great potential to relieve headache and migraine pain [10].
Who Should Avoid Vital Plan?
Vital Plan contains a low level of THC, making it unsuitable if you must undergo regular drug tests.
Potential Side Effects
CBD, some terpenes, and THC can have a sedative effect, which may be unwanted depending on the time of day you take it.
Summary
Vital Plan is a terpene-rich CBD oil that provides you with the best of the entourage effect. Thanks to this synergistic, anti-inflammatory effect, you may find relief from painful conditions such as migraine.
Charlotte’s Web is a good choice if you’re new to taking CBD, with dosages starting from as little as 7mg. If anxiety and stress keep you awake, this oil could be the right choice for you, with clinical studies confirming the beneficial effects of Charlotte’s Web hemp plant extract on stress, sleep, and general well-being [4].
Who Should Avoid Charlotte’s Web?
Charlotte’s Web is high in the sedative terpene myrcene, which you should avoid if you already take sedatives or experience fatigue.
Potential Side Effects
CBD and other cannabinoids and terpenes in Charlotte’s Web can cause sedation, making it unsuitable for daytime use even if you don’t take other sedatives or have normal energy levels.
Summary
Charlotte’s Web is a distributor of hemp and cannabidiol products known for their high-quality and all-natural components. The company offers a diverse selection of CBD oils, capsules, and other hemp-derived products that may help with exercise-induced inflammation, sleep cycles, daily stress, calmness, and focus.
99{fe463f59fb70c5c01486843be1d66c13e664ed3ae921464fa884afebcc0ffe6c} pure CBD.
Large product selection.
US Hemp Authority certified.
Cons
Not third-party CGMP certified.
Unflavored.
Who Is Medterra CBD Oil Best For?
Medterra could be right for you if you must completely avoid THC. Medterra CBD oil has many benefits, one of the most essential being its capacity to regulate our endocannabinoid system.
The unique 1:1 blend of CBD and CBG may benefit patients seeking to treat pain, especially neuropathic pain [5].
Who Should Avoid Medterra CBD Oil?
High-potency CBD oil may not be suitable if you take other sedative herbs or drugs or certain medications such as warfarin or lithium.
Potential Side Effects
Despite containing no THC, Medterra may still cause drowsiness and other side effects such as appetite changes and dry mouth.
Summary
Medterra offers CBD extracts sourced from certified organic hemp. The oils combine CBD, MCT, and natural flavors, offering support for mental and physical health.
At just two to three cents per mg of CBD, Lazarus Naturals gives you the best value for money, making it suitable for those on a budget.
Customer reviews show glowing remarks, with many saying the oil has helped them achieve a sense of calm, peace, and balance, improving their emotional well-being and general health.
The brand claims its full-spectrum tinctures offer effective combinations of active ingredients and organically derived fruit flavors such as Yuzu’s Japanese citrus flavor. In a study, Yuzu was found to have stress-relieving aromatherapeutic qualities, along with antioxidant, anticarcinogenic, anti-inflammatory, and anti-diabetic properties [6].
Who Should Avoid Lazarus Naturals?
Before using Lazarus Naturals High Potency CBD Tincture Yuzu, inform your doctor of all medications you’re currently taking, including prescription and over-the-counter. Citrus fruits can affect the way your medicines work by increasing or decreasing their effects [7].
Potential Side Effects
Citrus extracts can speed up or slow the clearance of pharmaceuticals, which affects their ability to benefit you.
CBD and other cannabinoids may also cause drowsiness and muscle relaxant effects.
Summary
Lazarus Naturals offers excellent value for money with its CBD oil—2,400mg—presently available for $60. This equates to a $0.025 cost per mg, which is less than other big brands in the CBD industry.
Absolute Nature CBD oil offers multiple potential therapeutic effects, such as stress relief, pain management, support for better sleep quality, and treating insomnia.
The company offers a 100{fe463f59fb70c5c01486843be1d66c13e664ed3ae921464fa884afebcc0ffe6c} money-back guarantee on all of its products. Customers who are dissatisfied with their purchase can return the unused product within 30 days of purchase and obtain a full refund. You can also return open products within 14 days of delivery.
Who Should Avoid Absolute Nature CBD?
If you’re taking sedatives or muscle relaxants, Absolute Nature CBD may have an additive effect, so use caution or avoid the product.
Potential Side Effects
CBD, CBG, and other cannabinoids present in Absolute Nature CBD can have sedative or excessive muscle relaxant properties.
Summary
Absolute Nature offers a range of CBD products that are 100{fe463f59fb70c5c01486843be1d66c13e664ed3ae921464fa884afebcc0ffe6c} natural, vegan, eco-friendly, and third-party lab-tested.
10. Fab CBD – Best CBD Oil for High Blood Pressure
PAID CONTENT
Pros
CO2 extraction method.
Third-party tested.
Variety of choices.
Cons
Only available in full-spectrum.
Less information is provided on the packaging.
Low supply.
Who Is Fab CBD Best For?
Fab CBD products might be a good choice if you have hypertension. For instance, the Fab CBD Sleep Gummies contain L-theanine, which has been shown to lower blood pressure in laboratory research [8].
Additionally, CBD itself has been shown to have vasodilator properties, which benefit hypertensive patients by increasing the width of arteries [9].
Who Should Avoid Fab CBD?
With only full-spectrum options available, Fab CBD is best avoided if you must stick to zero-THC extracts. Supply issues may affect you if you cannot miss a dose.
Potential Side Effects
The low levels of THC may increase the ability of CBD to cause drowsiness and dry mouth. If you’re sensitive but decide on Fab CBD, taking it at night is advisable.
Summary
Fab CBD products may lower hypertension and its symptoms, such as chest pain, headache, and trouble sleeping. With high concentrations of CBD and the inclusion of other ingredients such as L-theanine, in some products, you may find effective relief from anxiety and related issues.
Understanding CBD Oil and Anxiety Management
Approximately 40 million adults in the United States are estimated to be affected by anxiety disorders, the most frequent type of mental illness [11].
CBD, a cannabinoid found in the Cannabis sativa plant, is a non-psychoactive chemical that can treat anxiety disorders. However, any cannabis plant containing more than 0.3{fe463f59fb70c5c01486843be1d66c13e664ed3ae921464fa884afebcc0ffe6c} THC is classified as marijuana under federal law and doesn’t receive legal protection under this legislation. Consult your healthcare provider to see whether CBD oils can help you control your anxiety.
How Does CBD Help With Anxiety?
The central nervous system is densely packed with cannabinoid receptors; they influence the functioning of our brain cells by regulating the release of neurotransmitters. Deficiencies in natural cannabinoids may increase the risk of developing PTSD and depression [12].
According to the authors of a 2015 research, CBD interacts with the cannabinoid type 1 receptor (CB1R), the serotonin 5-HT1A receptor, and other brain receptors that regulate fear and anxiety-related behaviors [13]. As demonstrated by these findings, CBD may have potential as a treatment for acute anxiety symptoms.
Preclinical and clinical evidence also supported CBD’s efficacy in treating a wide range of anxiety disorders, including:
Social Phobia or Social Anxiety Disorder (SAD).
Obsessive-Compulsive Disorder (OCD).
Generalized Anxiety Disorder.
Post-Traumatic Stress Disorder (PTSD).
Panic Disorder (PD).
How Long Does CBD Oil Take to Work for Anxiety?
CBD’s immediate effects typically take 30 to 120 minutes to take effect. However, long-term effects may take several weeks to manifest themselves.
It turns out that CBD is not a one-size-fits-all solution. Numerous variables—including the dose you take, the form (full-spectrum CBD oil, broad-spectrum CBD oil, or CBD isolate), and your weight—can have an impact on how long it takes for CBD to begin working.
The Entourage Effect
The entourage effect refers to the heightened benefits of CBD when numerous compounds work synergistically rather than alone.
Monoterpenes, diterpenes, triterpenes, and sesquiterpenes are all key components in cannabis resin that give it its distinct aroma. They can also alter the therapeutic qualities of different cannabis chemotypes due to their capacity to quickly permeate cell membranes and the blood-brain barrier [14].
Dosage and Potency
CBD’s potential to alleviate anxiety may follow what scientists refer to as a “dose-response curve.” Simply put, the curve depicts the relationship between dose size and response.
A study found that higher doses of CBD are more effective at reducing anxiety—but not too high [15]. Before a public speaking exam, participants were given varied CBD dosages by the researchers. A 300mg dose of CBD was found to reduce subjective anxiety markers considerably. This decline did not occur with the 150mg, 600mg, or placebo CBD dosages.
Body Weight
The amount of CBD you need to take in order to reap the advantages is directly proportional to your body fat. People who are overweight will require a higher dose of CBD oil to feel the effects, and body fat will also influence how long CBD lingers in your system.
While CBD doesn’t need to build up in your body to work, however, it does become stored in fat cells and will stay in your body even after the effects of CBD have worn off.
CBD Oil vs. Anxiety Medication
CBD is seen as a more natural alternative to pharmaceutical anxiety medications, with many CBD products coming from certified organic hemp plants, grown and cultivated without pesticides or herbicides.
Conventional anti-anxiety medications are frequently seen on lists of the most commonly abused pharmaceuticals. Due to the euphoric feelings they often induce, users may quickly develop tolerance and, as a result, become more reliant on using them to maintain control of their anxiety.
According to one study, taking drugs to treat insomnia and anxiety raises the risk of death by 36{fe463f59fb70c5c01486843be1d66c13e664ed3ae921464fa884afebcc0ffe6c}.
Furthermore, the correct diagnosis of an anxiety condition is the first step toward treatment. If the initial treatment is unsuccessful and someone receives a wrong diagnosis, the repercussions can be catastrophic, depending on the underlying illness.
Receiving the wrong treatment can also result in a person suffering all of the medication’s negative effects while receiving none of the benefits, creating unnecessary distress and worry while leaving the underlying problem unaffected.
Benefits and Risks of Using CBD for Anxiety
CBD products come with risks and benefits, which are essential to be aware of before use.
Benefits
CBD is claimed to benefit a number of symptoms related to anxiety:
Effective, safe relief of anxiety. While conventional medication may increase the risk of mortality, CBD oil can reduce anxiety with a milder risk profile.
Reduce neuropathic pain and migraine by calming inflammation and regulating neurotransmitters.
Reduction in elevated blood pressure through regulating smooth muscle contractions.
Regulation of the stress response, which may soothe post-traumatic stress.
Support better sleep quality if anxiety keeps you awake at night.
Risks
CBD-based anxiety products have yet to be approved by the FDA.
Dosage and potency vary among products due to the lack of FDA regulation.
Large doses of THC are associated with increased anxiety and may trigger a positive result for cannabis on a drug test.
Besides legal issues, we ensured that every CBD oil reviewed here doesn’t have a high enough THC:CBD ratio to cause anxiety.
Potential Side Effects of CBD Oil
CBD is considered safe and well-tolerated by the World Health Organization. However, it does have some adverse effects, including:
Dry mouth.
Drowsiness.
Diarrhea.
Changes in appetite.
Low blood pressure.
Nausea.
Vomiting.
Pregnant or breastfeeding women should avoid using any cannabis product, including CBD.
Additionally, CBD products may potentially enhance the risk of adverse effects when combined with certain medications. Some regularly prescribed medicines, such as warfarin, lithium, sertraline, tramadol, codeine, valproic acid, carbamazepine, and captopril, may cause interactions. Consult your doctor prior to using CBD in conjunction with other drugs to avoid interactions.
Qualities of a Good CBD Oil for Anxiety
When picking a CBD oil for anxiety, it’s important to do your research to ensure that you’re receiving the most up-to-date and accurate information regarding high-quality CBD oils.
Here are some things to consider:
THC:CBD Ratio
For anxiety, the optimal THC:CBD ratio is 1:1, with one or more parts CBD to each part THC. When the THC:CBD ratio is greater than 1:1, anxiety may be exacerbated.
When CBD and THC are used together, they have a lot of synergies. In recent years, there has been a rising interest in determining the optimal ratio of each cannabinoid for treating various health issues, including anxiety disorders. Before buying, keep in mind that THC-dominant concentrates induce euphoria and sedation, so care needs to be taken.
Dosage
No matter what condition you’re aiming to treat with CBD, giving yourself an adequate dosage is important, otherwise, it may not be effective. As previously reported, the use of a 300mg dosage of CBD was found to significantly lower subjective anxiety signs.
Third-Party Testing
In today’s market, third-party CBD testing is critical. A survey found that over 70{fe463f59fb70c5c01486843be1d66c13e664ed3ae921464fa884afebcc0ffe6c} of cannabidiol extracts sold online are mislabeled, containing either significantly more or less CBD than advertised.
The goal of third-party or independent lab testing is to give an objective assessment of CBD oil brands. These tests are used to determine a CBD sample’s quality, purity, and potency.
Tolerance
Given that CBD is a supplement that people use on a regular basis, there are concerns about the potential of developing a tolerance.
However, regular CBD users don’t appear to develop a tolerance. This is due to the fact that CBD and THC bind to CB1 receptors in different ways. As a result, CBD doesn’t desensitize these receptors when it binds to them.
How To Use CBD Oil for Anxiety
CBD oil for anxiety can be consumed in a variety of ways:
As an oil or tincture: CBD oils and tinctures can be taken straight beneath the tongue. Drop a CBD dose under your tongue and hold it there for a minute before swallowing.
In a capsule: CBD capsules may be beneficial for individuals seeking to maintain a regular level of the substance in their body. It may take up to 30 minutes after ingesting the capsule to feel the effects.
In a smoothie: If you’re struggling with the strong earthy flavor of some CBD oil combinations, mix half a teaspoon of CBD oil into your morning smoothie for a calming start to the day.
Keep in mind that if you put your CBD oil in a smoothie or in a coffee with almond milk, sugar, or anything else that needs to be digested, it will take longer for the CBD to kick in than if you put a few drops under your tongue.
What Is the Best CBD Oil for Dogs With Anxiety?
Cornbread’s Pet CBD Oil is the best product we found for dogs and cats with anxiety.
Dogs, like humans, have an endocannabinoid system that includes cannabinoid receptors and endocannabinoids. This means they can benefit from organic CBD oil in the same way that humans do. CBD works by attaching to cannabinoid receptors, allowing natural equilibrium and creating a state of balance inside the body.
Many ailments can be alleviated with this balance, including anxiety. Consequently, CBD dog treats are an all-natural solution that can benefit your four-legged friend’s health and well-being for years to come.
How Much CBD Oil Should I Give My Dog for Anxiety?
For dogs with anxiety, a dose between 1 and 5mg for every 10lbs of body weight is generally recommended.
Consider a dose in the midpoint of the recommended range and keep an eye out for sedative effects. Within an hour, you should notice a difference. If not, you may wish to provide additional CBD to bring the whole dose to the recommended maximum.
Once you’ve administered the correct dose, your dog should not appear lethargic; rather, it should appear calmer with less panting, pacing, and whining.
CBD Dosages and Positive Drug Tests
Drug tests don’t screen for cannabidiol. However, many CBD products contain trace amounts of THC, marijuana’s primary active component. If sufficient THC is present, it will be detected on a drug test. This begs the question: Is CBD legal?
CBD products having greater than 0.3{fe463f59fb70c5c01486843be1d66c13e664ed3ae921464fa884afebcc0ffe6c} THC are classified as marijuana under federal law but are legal under certain state regulations. Always verify state legislation, particularly when traveling. Additionally, keep in mind that the FDA hasn’t approved nonprescription CBD products and that some products may be labeled incorrectly.
Our Ranking Methodology
We weighed the benefits and drawbacks of each of the CBD brands and oil products on the market to pick the best CBD for anxiety. We focused on nine criteria to rank each product in an unbiased, transparent, and accurate manner.
Claims and Scientific Evidence
The results of a 2019 case study, which included 103 adults, revealed that CBD appears to be beneficial when it comes to reducing self-reported anxiety.
In a double-blind trial, participants were randomly assigned to receive oral CBD at doses of 150 mg, 300 mg, 600 mg, or placebo. A 300 mg dose of CBD oil was found to considerably reduce anxiety symptoms.
Third-Party Lab Testing
A study conducted by researchers from the University of Pennsylvania School of Medicine found that approximately 70{fe463f59fb70c5c01486843be1d66c13e664ed3ae921464fa884afebcc0ffe6c} of all CBD oil brands marketed online are mislabeled or contain hazardous amounts of THC, posing a major risk to patients and consumers.
Because a third-party company is less likely to mislead on its lab tests, this technique boosts a CBD manufacturer’s credibility. Many of these businesses are well-known in the industry, and they have a reputation to uphold by doing regular, accurate testing.
Organic Certification
CBD oils of high grade are derived from organically-produced hemp. Only a handful of CBD oils are certified organic by credible agencies like the USDA, according to a review of most CBD oils.
Brand Reputation
The best CBD oils for anxiety disorders are produced by trained experts such as pharmacists, doctors, and other licensed professionals. Companies that have such expertise in their workforce are generally trustworthy.
Additionally, we combed through reviews of candidates for the best CBD oil for anxiety on a variety of websites, including the company’s website and various social media platforms.
THC Content
THC and CBD appear to have different impacts on anxiety disorders. Pure THC appears to reduce anxiety at low dosages while increasing anxiety at high doses. Products with a 1:1 ratio have minor psychoactive effects and can be extremely efficient at reducing the symptoms of anxiety disorders.
These products allow the customer to benefit from THC’s more intense calming benefits while also reducing the risk of experiencing THC’s negative effects.
Carrier Oil Used
Carrier oil is critical for increasing the potency of CBD oils. Despite the fact that many CBD oils and other CBD products are water-based, some companies add MCTs and other fatty oils. Carrier oils boost CBD oil quality, absorption, and delivery. As a result, they are an important feature to consider when rating CBD oils.
Full Spectrum Products
Broad-spectrum CBD oil and CBD isolate enables users to reap the benefits of CBD in combination with other forms of cannabis extract. However, neither of these options utilizes all of the beneficial qualities inherent in the cannabis plant to the extent that full-spectrum CBD oils do.
Extra Ingredients
In addition to CBD and THC, the cannabis plant includes over 100 cannabinoids as well as a slew of other compounds known as terpenes and flavonoids.
A full-spectrum hemp extract CBD oil, for example, will include all-natural hemp constituents such as aromatic terpenes, which enhance the effects of CBD and other cannabinoids, flavonoids, omega acids, phytonutrients, and phytocannabinoids like CBG and CBC.
Flavors Available
Without flavorings, CBD oil has an earthy, grassy flavor, which is why manufacturers are creating a variety of flavored CBD oils to improve the taste of the product. Top-rated CBD companies use flavors that have been approved by the USDA Organic standards.
FAQs on CBD Oil for Anxiety
Here are the answers to some of the most frequently asked questions about CBD oil for anxiety.
Does CBD Oil Remove Anxiety?
Yes, preliminary evidence from human trials including both healthy volunteers and people suffering from a social anxiety disorder, suggests that CBD has anxiolytic properties. As a result, it can be used as a potential treatment for generalized anxiety disorder, post-traumatic stress disorder, obsessive-compulsive disorder, panic disorder, and social anxiety disorder.
What Is the Most Effective Form of CBD for Anxiety?
Sublingually administered (under the tongue) CBD oil, like Cornbread Hemp, is the most effective form of CBD for anxiety, having the highest and fastest absorption rate of the cannabinoid.
What’s the Best CBD Oil for Anxiety? Our Verdict
Cornbread, Spruce, and Nuleaf would be our top recommendations, informed by our research. For pets with anxiety, Pet CBD Oil is uniquely suited to ease the symptoms without ‘zombie-ying out’ your pet.
CBD oil is an effective way to treat a variety of mental disorders, such as anxiety, panic, OCD, and more. However, choosing the right oil for you, with the correct THC:CBD ratio is crucial to get the most out of the oil without the negative effects of THC.
All of the CBD oil for anxiety we included in our list are certified organic and third-party lab-tested to ensure maximum quality. Keep in mind that if you often undergo drug testing, choosing a THC-free CBD oil is essential. Otherwise, you risk testing positive for marijuana.
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References:
Esther M. Blessing, Maria M. Steenkamp 2, Jorge Manzanares, Charles R. Marmar. “Cannabidiol as a Potential Treatment for Anxiety Disorders.” Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics, U.S. National Library of Medicine, https://pubmed.ncbi.nlm.nih.gov/26341731/.
Maayah, Zaid H., et al. “The Molecular Mechanisms That Underpin the Biological Benefits of Full-Spectrum Cannabis Extract in the Treatment of Neuropathic Pain and Inflammation.” Biochimica Et Biophysica Acta (BBA) – Molecular Basis of Disease, Elsevier, 19 Mar. 2020, https://www.sciencedirect.com/science/article/pii/S0925443920301162.
Russo B. Ethan. “TAMING THC: Potential Cannabis Synergy and Phytocannabinoid-Terpenoid Entourage Effects.” British Journal of Pharmacology, Blackwell Publishing Ltd, Aug. 2011, https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC3165946/.
“Radicle Aces: Everything You Need to Know.” Radicle Science, https://radiclescience.com/resources/radicle-aces-everything-you-need-to-know.
Gemayel Lee, Brittany Grovey, Tim Furnish, Mark Wallace. “Medical Cannabis for Neuropathic Pain.” Current Pain and Headache Reports, U.S. National Library of Medicine, https://pubmed.ncbi.nlm.nih.gov/29388063/.
Tamaki Matsumoto, Tetsuya Kimura, Tatsuya Hayashi. “Aromatic Effects of a Japanese Citrus Fruit-Yuzu (Citrus Junos Sieb. Ex Tanaka)-on Psychoemotional States and Autonomic Nervous System Activity during the Menstrual Cycle: A Single-Blind Randomized Controlled Crossover Study.” BioPsychoSocial Medicine, U.S. National Library of Medicine, https://pubmed.ncbi.nlm.nih.gov/27103942/.
Saito M;Hirata-Koizumi M;Matsumoto M;Urano T;Hasegawa R; “Undesirable Effects of Citrus Juice on the Pharmacokinetics of Drugs: Focus on Recent Studies.” Drug Safety, U.S. National Library of Medicine, https://pubmed.ncbi.nlm.nih.gov/16048354/.
Matsuoka, Kanako et al. “l-Theanine Protects Bladder Function by Suppressing Chronic Sympathetic Hyperactivity in Spontaneously Hypertensive Rat.” Metabolites vol. 11,11 778. 14 Nov. 2021, doi:10.3390/metabo11110778
Pacher, P, et al. “Cardiovascular Pharmacology of Cannabinoids.” Handbook of Experimental Pharmacology, U.S. National Library of Medicine, 2005, https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC2228270/.
Eric P. Baron. “Medicinal Properties of Cannabinoids, Terpenes, and Flavonoids in Cannabis, and Benefits in Migraine, Headache, and Pain: An Update on Current Evidence and Cannabis Science.” Headache, U.S. National Library of Medicine, https://pubmed.ncbi.nlm.nih.gov/30152161/.
“Facts & Statistics: Anxiety and Depression Association of America, ADAA.” Facts & Statistics | Anxiety and Depression Association of America, ADAA, https://adaa.org/understanding-anxiety/facts-statistics.
Hill, Matthew N et al. “Integrating Endocannabinoid Signaling and Cannabinoids into the Biology and Treatment of Posttraumatic Stress Disorder.” Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology vol. 43,1 (2018): 80-102. doi:10.1038/npp.2017.162
Esther M. Blessing et al. “Cannabidiol as a Potential Treatment for Anxiety Disorders.” Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics, Springer US, Oct. 2015, https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC4604171/.
Pavlovic Radmila, et al. “Quality Traits of ‘Cannabidiol Oils’: Cannabinoids Content, Terpene Fingerprint and Oxidation Stability of European Commercially Available Preparations.” Molecules (Basel, Switzerland), MDPI, 20 May 2018, https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC6100014/.
Ila M. Linares, Antonio W. Zuardi, Luis C. Pereira, Regina H. Queiroz, Raphael Mechoulam, Francisco S. Guimarães, José A. Crippa. “Cannabidiol Presents an Inverted U-Shaped Dose-Response Curve in a Simulated Public Speaking Test.” Revista Brasileira De Psiquiatria (Sao Paulo, Brazil : 1999), U.S. National Library of Medicine, https://pubmed.ncbi.nlm.nih.gov/30328956/.
Leading Gamers – ENDOCA, Isodiol, Medical Cannabis, Aurora Hashish, CBD American Shaman
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Hemp oil extracts have historically been employed all around the world as medication. A big physique of proof has indicated that the advantages of CBD hemp oil can alleviate several illnesses. Endoca maintains the biochemical equilibrium inside the hemp vegetation to maximize the advantageous effects of its natural and organic CBD oil. Because of to the COVID-19 pandemic, the global CBD Oil marketplace dimensions is approximated to be well worth US$ 301.6 million in 2021 and is forecast to a readjusted dimensions of US$ 1455 million by 2028 with a CAGR of 25.{fe463f59fb70c5c01486843be1d66c13e664ed3ae921464fa884afebcc0ffe6c} all through the forecast period of time 2022-2028.
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The cannabis Sativa plant provides cannabidiol (CBD) and tetrahydrocannabinol (THC) however, THC is much better recognized considering that it leads to people to get intoxicated. Even though distinct dates have been proposed, it is commonly agreed that the plant’s medicinal or ritualistic use dates again to about 750 B.C.E. in Central Asia.
Among the additional than 100 cannabinoids in cannabis, cannabidiol (CBD) and tetrahydrocannabinol (THC) are the most well-acknowledged. THC is psychoactive having said that, the psychoactivity of CBD is debatable. Stress and anxiety may perhaps be manufactured even worse by THC, but whether or not CBD aids or hinders is unclear. It has been shown that THC might induce dependency, and CBD is now remaining investigated for its possible to aid recovery.
Claims of CBD
Commercials promoting CBD emphasize that it will ease anxiety, despair, and PTSD signs and symptoms. It’s also advertised as a snooze aid. CBD claims to be “non psychoactive,” this means that buyers may perhaps get high-high-quality healthcare positive aspects without receiving significant (or the midnight pizza munchies).
Advertising and marketing is multiplying like hemp seeds all through the United States. There appears to be to be no products or spot off-restrictions to CBD, with oils, nasal sprays, lollipops, and even suppositories all creating an overall look.
Best Benefits of CBD Oil
Research suggests that the favorable consequences of pure CBD may possibly be far-reaching. Healthcare cannabis and CBD oil at Magu can enable you speak to accredited professional medical gurus who can prescribe alternative hashish therapies for your precise issue and produce them to you.
The hashish system, a network of enzymes, neurotransmitters, and receptors vital to properly forming the mind, need to be taken into account to have the full extent of these benefits.
Suffering Aid
As long again as 2900 B.C., men and women have been using cannabis to alleviate soreness. New scientific investigate has pinpointed cannabidiol (CBD) as the compound dependable for cannabis analgesic advantages. The endocannabinoid system is a large network of receptors and enzymes in the human system that regulates processes as varied as snooze, hunger, agony perception, and immunological response.
Neurotransmitters known as endocannabinoids are normally manufactured by the body and connect to cannabinoid receptors. The effects of CBD on endocannabinoid receptor perform, swelling, and neurotransmitters propose it may perhaps be practical for dealing with long-term ache.
Many sclerosis (MS) and arthritic discomfort have both of those been demonstrated to answer effectively to a combination of cannabidiol (CBD) and tetrahydrocannabinol (THC) in human trials. A lot more higher-quality trials are necessary to assess CBD’s usefulness in suffering administration. Having said that, professionals are cautiously hopeful that it may well be useful in dealing with many varieties of discomfort, significantly when paired with THC.
Mood Conditions
Anxiousness and mood diseases, this kind of as melancholy or article-traumatic worry ailment, can affect your working day-to-working day everyday living and routinely result in bodily and psychological worry. It is way too quickly to comprehend the entire range of outcomes that CBD may perhaps have on anxiousness and temper disorders. However, personal investigate tends to indicate that CBD may well have favorable benefits, shifting from analyze to analyze.
A analyze included 57 men who were offered oral CBD or a placebo ninety minutes prior to getting portion in a simulated exam of their general public talking skills. Researchers found that a dose of 300 milligrams of CBD noticeably minimized the participants’ social anxiousness concentrations even though taking the take a look at.
Cancer-Relevant Issues
Nausea, vomiting, and bodyweight decline, widespread side outcomes of chemotherapy remedy, might be lessened by CBD. The Food and drug administration authorized 3 prescription drugs derived from cannabis in the hopes that they can reduce some of these signs or symptoms and stimulate hunger in these with AIDS. These medications not only consist of CBD but also various degrees of THC or synthetic THC.
Even so, there is evidence from selected research that CBD might enable lessen the measurement of tumors and may possibly help block the unfold of malignant cells in several cancers. To fully have an understanding of the impression CBD has on the lots of distinct forms of most cancers, further human clinical research are required, just as is the circumstance with other investigation fields.
Neurological-Relevant Disorders
Researchers assume that individuals with neurological complications could possibly advantage from CBD for the reason that of the compound’s ability to interact with the endocannabinoid program and other mind signaling programs. Even so, CBD has been thoroughly investigated to deal with neurological sicknesses, which include epilepsy and many sclerosis.
Whilst scientific studies in this area are nonetheless in their infancy, early results have been encouraging. Repercussions of CBD medication, this kind of as seizures, fever, and lethargy, ended up reported in some members in each trials. Many added neurological issues have also been investigated for doable efficacy in treatment method with CBD.
For individuals with Parkinson’s illness, for occasion, CBD therapy has been established in many trials to improve each traits of lifetime and sleep. Even so, industry experts say there is presently a dearth of trustworthy info. Hence, there is at this time not substantially data to propose CBD for dealing with PD.
Conclusion
Study on the consequences of cannabidiol (CBD) oil on a wide variety of health care health conditions, from panic to neurological illnesses, has been conducted. In addition, it has the opportunity to improve cardiac well being and alleviate suffering in specified men and women. Keep in mind that some of these claimed health and fitness rewards are tied to using CBD in conjunction with THC and not CBD by itself.
From a medical standpoint, your dog can’t fatally overdose on CBD. That’s because CBD doesn’t mess with the brain stem areas responsible for respiration.
That being said, a dog can overdose on CBD oil in the sense that it will experience a range of side effects.
Fortunately, these are mild and non-life-threatening — and almost inexistent in normal doses.
But let’s say you gave your dog too much CBD oil.
What now?
Should you be worried? Does a CBD overdose require a check-up with the vet?
You’ll find the answer below. Today, we explain the ins and outs of the pharmacological risks of CBD for dogs.
CBD and Dog Overdose: Highlights
CBD is a natural modulator of the endocannabinoid system (ECS) — a vast neurochemical network common among all mammals.
The ECS regulates the most important biological functions, such as sleep, memory, mood, appetite, pain, immune response, body temperature, neurogenesis, fertility, etc.
Giving your dog CBD oil can improve its quality of life by supporting homeostasis (balance) throughout the body.
CBD can also address several pet symptoms and ailments, which is why dog parents are turning to it as an alternative to conventional treatments (or as supportive therapy)
CBD is generally considered safe and well-tolerated by animals and humans. A dog can’t lethally overdose on it.
However, CBD can be overdosed and cause a few mild side effects, such as dry mouth, lethargy, appetite fluctuation, and diarrhea.
If you notice any signs of CBD in your dog, calm down and be patient. The side effects should disappear within a few hours.
Any alarming signs indicative of toxicity caused by consuming a contaminated CBD product require immediate veterinary care.
Can a Dog Overdose on CBD Oil?
If you’re thinking about a classic type of overdose — when someone takes too much of a given substance and dies — the answer is no.
But can your dog experience negative side effects when you give them too much CBD oil?
Of course.
The good news is that, in the worst-case scenario, the doggie will need to sleep them off.
CBD doesn’t interact with brainstem receptors and doesn’t disrupt breathing.
Not to mention that dogs have a certain threshold of CBD they can utilize. The rest will come out with a poo.
The WHO explained in a 2018 review on CBD that large doses seem to trigger diarrhea, lethargy, and drowsiness in dogs. However, they also concluded that CBD products are generally safe and well-tolerated by humans and our four-legged friends.
Researchers in a 2019 study also stated that cannabinoids have a favorable safety profile when administered orally.
Long story short, it’s safe to assume that CBD overdoses are theoretically possible, but most of them involve benign side effects.
As long as you stick to the recommended dosage, CBD is safe for your dog.
The Difference Between Overdose vs. Toxicity in Dogs
An overdose occurs when a safe substance breaches the safe dosage threshold, while toxicity may be triggered even by tiny doses of unsafe substances.
Your dog can overdose on many products, including CBD. However, not all overdoses are the same, but from a medical standpoint, you shouldn’t worry too much about giving your dog too much CBD oil.
Pet poisoning or toxicity isn’t the same as overdose. Toxicity occurs when a dog is given a substance that doesn’t produce any benefits regardless of the dose — but can be toxic.
This poison could be a plant in your home, a marijuana product, mushrooms, or human medications.
If you want to give your dog CBD oil, you should opt for hemp-derived products. They contain 0.3{fe463f59fb70c5c01486843be1d66c13e664ed3ae921464fa884afebcc0ffe6c} THC or less, so they won’t get your dog high.
Never give your dog any marijuana product — it can drive your dog paranoid, cause a racing heart, induce a panic attack, or make the dog vomit.
If your dog accidentally consumed a marijuana edible, take them to the vet right away.
Can CBD Harm or Kill Your Dog?
No, CBD won’t harm or kill your dog. Theoretically speaking, since pet CBD products can legally contain 0.3{fe463f59fb70c5c01486843be1d66c13e664ed3ae921464fa884afebcc0ffe6c} THC or less, and THC can be toxic to dogs, consuming an extremely large dose of CBD could result in THC toxicity.
However, this could only happen if you force-fed your dog with CBD or give them a giga-chunk of CBD wax — both actions seem unimaginable for loving dog parents.
You need to watch out for some CBD products, though. The CBD market lacks regulations in terms of manufacturing and labeling standards. According to various studies, around 60{fe463f59fb70c5c01486843be1d66c13e664ed3ae921464fa884afebcc0ffe6c} of CBD products available on the market are mislabeled or contaminated with excessive amounts of THC.
THC toxicity in dogs includes symptoms like racing heart, anxiety, sensitivity to loud noises, touch, and light, extreme lethargy, and dilated pupils.
Dogs with THC toxicity should be taken immediately to the veterinarian. Your vet will be able to provide it with adequate treatment.
Depending on the severity of intoxication, the vet may recommend hospitalization to make sure the dog receives an adequate amount of fluids and additional care.
To wrap it up, a dog can’t fatally overdose on CBD, and as long as you give them hemp-derived CBD oil or pet treats, the side effects of taking too much CBD should be mild.
What Happens When a Dog Overdoses on CBD Oil?
Sleepiness is the most common reaction to a CBD oil overdose. This effect stems from lightheadedness, low blood pressure, and drowsiness. To understand the safety of CBD oil, pet parents should become familiar with how CBD works in dogs.
CBD produces its therapeutic effects by interacting with the endocannabinoid system (ECS). The ECS is made of cannabinoid receptors, endocannabinoids (CBD- and THC-like molecules), and enzymes.
The ECS promotes and helps maintain homeostasis throughout the body, controlling a wide range of essential functions, such as pain, immune function, body temperature, sleep, appetite, fertility, memory, neurogenesis, etc.
CBD modulates the ECS by acting on its enzymes and naturally increasing the concentrations of endocannabinoids in the bloodstream. They also enhance receptor activity.
CBD also acts on over 65 molecular pathways, hence its therapeutic versatility. However, the complex nature of its effects makes it able to calm down a dog’s nervous system to a great extent — causing the aforementioned lethargy.
Side Effects of CBD Oil Overdose in Dogs
High doses of CBD oil in dogs are associated with an increased risk of adverse reactions.
Depending on the dog’s weight, metabolism, and CBD dosage, your dog may experience the following side effects:
Dry mouth
Lethargy
Diarrhea
Lowered blood pressure
Changes in liver enzymes
CBD is also a potent inhibitor of the cytochrome P450 (CYP450) enzyme system, which metabolizes 60–80{fe463f59fb70c5c01486843be1d66c13e664ed3ae921464fa884afebcc0ffe6c} of pharmaceutical drugs. If you give your dog other medications, consult the use of CBD oil with your veterinarian.
Depending on the type of interaction, CBD can increase or decrease the drug levels in your dog’s bloodstream, leading to toxicity or subtherapeutic effects.
Talking to the vet will help you space out the dosages and schedule for both compounds so that no negative interactions occur.
How to React If Your Dog Overdoses on CBD Oil
Since the nature of CBD overdoses is mild, you won’t need to take your dog to the vet most of the time. Just make sure they have access to drinking water and a calm spot to fall asleep for the duration of the effects.
However, when the dog suffers from THC toxicity, seek immediate veterinary care. The faster you act, the safer your pet will be. Mild cases usually require outpatient care, but more severe cases may call for hospitalization.
Should You Take Your Dog to Vet After a CBD Overdose?
If you suspect you might have given your dog too much CBD oil, call your vet and consult the issue. If your dog is just going through some normal lethargy, ask the vet for help with adjusting the dose of CBD oil.
Finding the right dosage should help you avoid such problems.
When a dog overdoses on CBD, it’s only considered an emergency case if the product contained significant amounts of THC, which is found in marijuana products for humans.
In a 2016 study, the authors confirmed that marijuana has toxic effects on dogs. The study mentioned that dogs are more sensitive to THC because they have more cannabinoid receptors in the brain compared with humans.
Again, take your dog to the vet if you notice any symptoms indicative of marijuana toxicity.
And keep your pot brownies out of their reach.
What’s the Recommended Dosage for Dogs?
CBD oils come in different potencies, so make sure to check the packaging and dosage instructions provided by the manufacturer.
The optimal dosage for dogs depends on their weight and metabolism. It’s a good idea to start with 1–2 mg of CBD for every 10 pounds of the dog’s weight.
It usually takes about 15–30 minutes after the intake to notice the effects. Some of the CBD will be absorbed by the sublingual membrane in the dog’s mouth, while the rest will travel to its bloodstream through the gut.
If this is your first time giving your dog CBD oil, remember to observe how they respond and look for possible side effects so that you can adjust the dosage accordingly.
Is CBD Addictive to Dogs?
There’s no evidence that CBD could make the dog addicted to it. The aforementioned report from the WHO made it clear that the abuse potential for CBD is the same as for a placebo.
However, even though CBD is a biologically appropriate supplement with a wide range of health benefits, you should always look for the best-quality products for your dog.
Best CBD Oils for Dogs
1. Royal CBD
Pros
Cons
Organic hemp from US farms
CO2 extraction
Suspended in MCT oil
Up to 500 mg of CBD per bottle
Full-spectrum CBD
Dog-friendly flavor
Rather expensive compared to similar products
Royal CBD is known for its award-winning formula for humans. Recently, the brand has upgraded its lineup with a new collection of CBD products for dogs.
Dog parents can choose from two strengths: 250 mg and 500 mg. The first option works better with smaller breeds, while the latter is more suitable for larger dogs.
Both variants come in the beloved flavor of all meat-eater: bacon.
These CBD oils contain the full spectrum of cannabinoids and terpenes, leveraging the entourage effect — a unique synergy between these ingredients that boosts the effectiveness of CBD.
2. Gold Bee
Pros
Cons
Organic, non-GMO hemp
Full-spectrum CBD
MCT carrier oil
600 mg CBD per bottle
No low-strength CBD oils for dogs
Limited supply available due to high demand
Gold Bee specializes in CBD products infused with superfoods. This unusual company makes CBD oils created with larger breeds in mind. The Gold Bee CBD pet oil contains 600 mg of total CBD, translating into 20 mg CBD per mL. If you have a smaller dog, this oil can be difficult to dose, but on the other hand, it may last you longer than low-strength options.
Similar to Royal CBD, all Gold Bee products are tested for potency and purity in a third-party laboratory, with batch-specific certificates of analysis available on the Gold Bee website.
CBD Overdose in Dogs is Real, But Should You Be Worried?
More often than not, there’s nothing to worry about when a dog overdoses on CBD oil.
The side effects of taking too much CBD include dry mouth, a drop in blood pressure, changes in appetite, and lethargy. Most of the time, your dog will be sleepy after a CBD overdose.
With marijuana products, it’s a different story. If you use marijuana-derived CBD oil or have some pot edibles in your kitchen, keep them in a safe place, away from the dog. Dogs may suffer from THC toxicity after ingesting marijuana. If you notice signs of intoxication in your dog, take them to the vet immediately.
Overall, as long as you choose the right product and stick to the recommended dosage, the side effects of CBD oil are non-existent.
Sources:
World Health Organization. (2017). Drugs (psychoactive): Cannabidiol (compound of cannabis). WHO.int. Retrieved from:(1)
Vaughn, D., Kulpa, J., & Paulionis, L. (2020). Preliminary Investigation of the Safety of Escalating Cannabinoid Doses in Healthy Dogs. Frontiers in veterinary science, 7, 51 (2).
Fitzgerald, K. T., Bronstein, A. C., & Newquist, K. L. (2013). Marijuana poisoning. Topics in companion animal medicine, 28(1), 8–12 (3).
Atalay, S., Jarocka-Karpowicz, I., & Skrzydlewska, E. (2019). Antioxidative and Anti-Inflammatory Properties of Cannabidiol. Antioxidants (Basel, Switzerland), 9(1), 21 (4).
Kaur, R., Ambwani, S. R., & Singh, S. (2016). Endocannabinoid System: A Multi-Facet Therapeutic Target. Current clinical pharmacology, 11(2), 110–117 (5).
de Almeida, D. L., & Devi, L. A. (2020). Diversity of molecular targets and signaling pathways for CBD. Pharmacology research & perspectives, 8(6), e00682 (6).
Iffland, K., & Grotenhermen, F. (2017). An Update on Safety and Side Effects of Cannabidiol: A Review of Clinical Data and Relevant Animal Studies. Cannabis and cannabinoid research, 2(1), 139–154 (7).
Brown, J. D., & Winterstein, A. G. (2019). Potential Adverse Drug Events and Drug-Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use. Journal of clinical medicine, 8(7), 989 (8).
Gyles C. (2016). Marijuana for pets?. The Canadian veterinary journal = La revue veterinaire canadienne, 57(12), 1215–1218 (9).
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