Tag: Supplements

  • Best Adderall Alternatives (2023 Update) Top Natural OTC Adderall Alternative Supplements

    Best Adderall Alternatives (2023 Update) Top Natural OTC Adderall Alternative Supplements

    Attention deficit hyperactivity disorder(ADHD) is a condition that affects cognitive brain function and brain health. It is characterized by symptoms like difficulty sustaining attention, impulsivity, and hyperactivity. ADHD can be treated with medication like Adderall, which helps to improve central nervous system function and enable better focus and concentration. 

    However, Adderall has several potential side effects, including insomnia, anxiety, and irritability. For people with ADHD, it is essential to weigh the risks and benefits of treatment options before making a decision. 

    One such treatment option that claims to be completely risk-free is an Adderall alternative. But what are Adderall alternatives? As the name goes, Adderall alternatives are prescription medications to treat attention deficit hyperactivity disorder. These alternatives to Adderall have become famous due to their efficacy and organic content. 

    So if you are looking for natural alternatives to Adderall, we have you covered. Today we have curated a list of the best Adderall alternatives that will boost cognitive function significantly upon daily usage. 

    The Best Natural Adderall Alternatives for 2023 

    We have conducted intensive research, and five alternatives to Adderall have blown our minds. Below, we will take a detailed look at these five products: 








    Mind Lab Pro 

    Mind Lab Pro is one of the most effective natural OTC Adderall alternatives to treat ADHD symptoms, improve mental clarity, positively alter brain chemistry and improve memory recall. 

    Modafinil 

    One of the most sought-after alternatives to Adderall, Modafinil can effectively boost brain function in just a few months. Modafinil works better than any prescription medication that claims to improve cognitive performance. 

    NooCube Brain Productivity 

    Manufactured by Wolfson Brands, this natural Adderall alternative eliminates brain fog and boosts multiple cognitive functions. Numerous customers have called it the most effective natural Adderall alternative. 

    Performance Lab Mind 

    Adderall substitutes cost a fortune, but Performance Lab Mind will give you the same benefits as other effective Adderall alternatives within a budget. From treating attention deficit disorder to reducing brain fog, this natural Adderall substitute does it all. 

    Onnit Alpha Brain 

    When looking for a natural alternative to Adderall, customers always look for user testimonials. Onnit Alpha Brain natural Adderall alternative has the most positive reviews on this list and is very trustworthy. 

    Mind Lab Pro 

    Mind Lab Pro
    Mind Lab Pro










    Product Overview 

    Form Of Supplement 

    Brain Pill 

    Ingredients Used 

    Lion’s Mane Mushroom (500 mg), Citicoline (250 mg), SharpPS® Green (100 mg), Bacopa monnieri (150 mg), Rhodiola rosea (50 mg), N-Acetyl-L-Tyrosine (175 mg), Maritime Pine Bark Extract (75 mg), Suntheanine® L-Theanine (100 mg) 

    Servings Per Container 

    30 

    Requirement Of A Prescription 

    None 

    Money-Back Guarantee 

    60-day 

    Pricing 

    Starts at $69.00 

    Mind Lab Pro is an excellent Adderall substitute. It has a good amino acid content to eliminate brain fog and cognitive decline. Amino acids are the building blocks of proteins and are essential for many biochemical processes in the body. These can also be found in some brain chemicals, including dopamine and norepinephrine. The absence of amino acids can cause brain fog and the deterioration of the brain cells. 

    Each Mind Lab Pro brain pill increases levels of dopamine and norepinephrine in the brain by blocking their reuptake into neurons. This allows more of these neurotransmitters to be available in the brain. 

    Dopamine is a neurotransmitter that plays a role in cognitive function, motor control, and motivation. Norepinephrine is another neurotransmitter that helps to regulate attention, focus, and mood. 

    Both of these neurotransmitters are important for maintaining mental performance and focus. However, levels of dopamine and norepinephrine can be low in people with ADHD. This can lead to symptoms like difficulty paying attention, impulsivity, and hyperactivity. 

    Opti Nutra Nutraceuticals is a leading manufacturer of nutritional supplements. The company uses state-of-the-art manufacturing processes and cutting-edge technology to produce dietary supplements like natural Adderall alternatives to improve brain health. 

    Opti Nutra Nutraceuticals uses branded, potent, standardized, and tested ingredients. The company has a team of highly qualified experts who use cutting-edge technology to develop safe and effective products. 

    Some benefits of using Mind Lab Pro are: 

    Enhanced Mental Energy 

    The human brain is a complex organ that requires a variety of nutrients to function optimally. Mind Lab Pro is one of the best natural supplements that provide brain cells with a wide range of vitamins and minerals that have been shown to boost mental energy and clarity. The formula includes vitamins B6, B12, and folate, essential for cognitive function, and minerals like magnesium and zinc, which have been shown to reduce mental exhaustion. 

    Regulation Of Alpha Brain Waves 

    Mind Lab Pro is one of the most effective Adderall alternatives that boost alpha brain waves to improve sleep and mental alertness. 

    The brainwave-boosting supplement helps to increase focus, concentration, and brain energy levels by stimulating the production of dopamine, norepinephrine, and serotonin. Mind Lab Pro also contains ingredients that support cognitive function and protect the brain from free radical damage. 

    Boosts Cerebral Blood Flow 

    Often, ADHD medications and natural Adderall substitutes do not exclusively focus on cerebral blood flow to and from the brain cells. However, Mind Lab Pro’s research team has included natural ingredients to boost blood flow and rejuvenate your damaged brain cells. 

    This process not only boosts brain function but also eliminates mental tiredness and improves memory recall. So, if you are looking for one of the top alternatives to Adderall, Mind Lab Pro is the perfect fit. 

    Modafinil 

    Modafinil 
    Modafinil 









    Product Overview 

    Ingredients Used 

    Lactose, Microcrystalline Cellulose, Pregelatinized Starch, Croscarmellose Sodium, Povidone, and Magnesium Stearate 

    Servings Per Container 

    NA 

    Requirement Of A Prescription 

    Prescription required 

    Money-Back Guarantee 

    NA 

    Pricing 

    It starts at $10 

    Many people suffer from neuropsychiatric disorders and irregular sleep schedules. For these individuals, finding the best Adderall alternative is essential for their well-being. 

    Modafinil has been shown to improve cognitive performance, memory recall, and brain function in general. Additionally, it can help those with irregular sleep schedules by providing them with the mental clarity and energy they need to get through their day. While Modafinil is a prescription drug, it is much safer than Adderall and other similar prescription drugs. 

    The brain chemicals such as catecholamine, serotonin, glutamate, gamma-aminobutyric acid, orexin, and histamine respond strongly to Modafinil. Additionally, each Modafinil brain pill enhances cognitive performance in several areas, including working memory, episodic memory, and other prefrontal and cognitive control-related tasks. 

    Modanifil natural Adderall substitute is sold under the brand name Provigil. Provigil is known for its natural supplements and medications, loyal customer base, trustworthy products, great value, and price. The company sources its ingredients ethically, which many customers appreciate. Provigil has a reputation for being a reliable and trustworthy company, which is why many people continue to use their products. 

    Some benefits of using Modafinil are: 

    Boosts Cognitive Function 

    Recent studies have shown that Modafinil can improve cognitive function in healthy individuals and help reduce brain fog. It does this by increasing dopamine levels and alpha brain waves. Modafinil also enhances blood flow to the brain, which helps to deliver oxygen and nutrients to the cells and keeps them healthy. 

    There are many benefits of taking Modafinil as a natural Adderall substitute, including improved brain health and cognitive function. If you are looking for a way to boost your brain power and get an edge on your competition, consider trying Modafinil. 

    Promotes The Working Of Brain Chemicals 

    Modafinil is a prescription medication that is an effective alternative to Adderall used to treat ADHD. Unlike Adderall, a stimulant, Modafinil promotes the working of brain chemicals by increasing levels of dopamine and norepinephrine. 

    This is important because these chemicals improve brain health and function. In addition, Modafinil has also been shown to improve task performance and memory in individuals with ADHD symptoms. Together, dopamine and norepinephrine eliminate mental tiredness and promote brain regeneration. 

    Improves Mental Energy 

    Modafinil is a medication used to promote mental energy. It is often used by people working long hours or demanding jobs. The drug works by increasing specific vitamins and minerals in the body, which are essential for mental energy. Mental energy is vital for overall health and well-being. It helps with focus, concentration, and memory. 

    NooCube Brain Productivity 

    NooCube Brain Productivity
    NooCube Brain Productivity









    Product Overview 

    Ingredients Used 

    Huperzia serrata (20 mg), Bacopa monnieri (250 mg), Lutemax® 2020, Resveratrol 99{fe463f59fb70c5c01486843be1d66c13e664ed3ae921464fa884afebcc0ffe6c} (anti-inflammatory), Pterostilbene (140 mcg), L-Theanine (100 mg), Alpha GPC (50 mg), L-Tyrosine (250 mg), Vitamin B 

    Servings Per Container 

    30 

    Requirement Of A Prescription 

    No prescription required 

    Money-Back Guarantee 

    60-day 

    Pricing 

    $59.99 

    NooCube is a very potent alternative to Adderall. It contains 13 scientifically-backed ingredients that improve cognitive performance, eliminate brain fog, and boost overall cognitive functions. 

    Unlike Adderall, a prescription drug used to treat ADHD, NooCube has no adverse effects. It also aids brain regeneration at the cellular level, promotes memory recall, and enhances problem-solving skills. The gut-brain axis, which supports the stimulation of neuronal activity in the brain, is the focus of NooCube. This part maintains your mental clarity and aids in decision-making. 

    With NooCube, Acetylcholine is broken down by enzymes called cholinesterases, and this process is thought to contribute to cognitive enhancement. NooCube ingredients include compounds that promote cholinesterases, which may help to prevent or slow down brain fog and sleepiness, which is often a result of excessive acetylcholine. 

    Wolfson Brands is the manufacturer behind NooCube, one of the market’s most popular organic supplement formulators. Known for its holistic approach to wellness and the body, Wolfson Brands drives positive change worldwide with its natural supplements. 

    NooCube is just one of many quality supplements they offer; others include D-Bal Max and PhenQ. What sets NooCube apart is its efficacy; users have reported feeling more alert and focused after taking it. Additionally, Wolfson Brands guarantees the quality of its products, so you can be sure you’re getting a high-quality supplement when you purchase NooCube. 

    Finally, all their products are reasonably priced, making them an excellent value. Whether looking for a natural way to improve your focus or find an edge in your busy life, each Wolfson Brands manufactures supplement is a great option worth considering. 

    Some benefits of using NooCube are: 

    Reduces Stress 

    NooCube has Lutemax, which reduces stress and can improve brain health and cognitive performance. NooCube works by modulating the activity of the neurotransmitter serotonin (a naturally occurring brain chemical), which helps to regulate mood and anxiety levels. 

    Stress can hurt brain health and cognitive performance. Chronic stress has been linked to decreased brain volume, reduced hippocampal function, and impaired executive functioning. 

    Stress also increases the risk of developing Alzheimer’s disease and other forms of dementia. Therefore, it is essential to find ways to reduce stress to protect the brain against cognitive decline. 

    In addition to reducing stress, NooCube’s natural alternative to Adderall has also improved user memory and learning. Therefore, NooCube may be a beneficial supplement for improving mental performance and protecting brain function. 

    Eliminates Brain Fog 

    NooCube is a brain-booster supplement that contains several vitamins and minerals essential for cognitive function, including biotin. Biotin is a water-soluble vitamin part of the B complex group of vitamins. It’s also known as vitamin H. Biotin plays a vital role in energy metabolism and helps the body convert fats, proteins, and carbohydrates into energy. 

    It’s also involved in the metabolism of fatty acids and amino acids. Biotin is essential for cell growth and the production of fatty acids. It’s also necessary for healthy skin, nails, and hair. Deficiencies of biotin can cause brain fog, fatigue, and depression. Supplementing with NooCube can help prevent these symptoms by ensuring you get enough biotin in your diet. 

    Performance Lab Mind 

    Performance Lab Mind 
    Performance Lab Mind 










    Product Overview 

    Form Of Supplement 

    Brain Pill 

    Ingredients Used 

    Cognizin (250MG), Sharp-Ps (100MG), L-Tyrosine (250MG), and Maritime Pine Bark Extract (75MG) 

    Servings Per Container 

    Start at 30 

    Requirement Of A Prescription 

    None 

    Money-Back Guarantee 

    30-day 

    Pricing 

    $69.00 

    Performance Lab Mind is a well-known Adderall substitute with 0 withdrawal symptoms and multiple natural ingredients used to treat ADHD for years. 

    It promotes brain cell regeneration, improves memory recall, enhances blood flow to the brain, and nourishes the cells. This supplement is designed to improve cognitive function and focus. It contains a blend of herbal extracts and nutrients that have been traditionally employed to support mental health. These herbs improve blood circulation to the brain, promote nerve cell growth, and enhance cognitive function. 

    Performance Lab is credited with the formulation of Mind. This lab produces some of the most advanced nutritional supplement systems available today to enhance short- and long-term health. Every Performance Lab product has top-tier ingredients created using cutting-edge healthy technology that performs better. 

    These advancements in nutrition technology are combined with the company’s ideal to create novel supplements that transform optimal performance nutrition. Performance Lab gets all its supplements from third-party lab tests as a part of its necessary quality check. This company has a global customer base with multiple positive user reviews for each product. 

    Some benefits of using Performance Lab Mind are: 

    Reduces Inflammation 

    The maritime pine bark extract in Performance Lab Mind is a potent anti-inflammatory agent that has been shown to promote cognitive health. The extract works by reducing the production of inflammatory cytokines and modulating the immune system’s activity. In addition, the maritime pine bark extract has antioxidant properties that protect the brain from damage caused by inflammation. 

    Improves Brain Health At The Cellular Level 

    Performance Lab Mind is a dietary supplement that contains phosphatidylserine (PS), a compound that plays a vital role in brain function. PS is a significant component of cell membranes and helps keep the cells intact and functioning correctly. It is involved in neurotransmission and contributes to the overall health of nerve cells. 

    PS has also been shown to improve cognitive function and memory, and it has also been shown to reduce age-related decline in brain function. Performance Lab Mind can help to improve brain function and protect against age-related degeneration. 

    Onnit Alpha Brain 

    Onnit Alpha Brain
    Onnit Alpha Brain










    Product Overview 

    Form Of Supplement 

    Brain Pill 

    Ingredients Used 

    Bacopa, Cat’s Claw Extract, Huperzia Serrata, Oat Straw Extract 

    Servings Per Container 

    Starts at 15 

    Requirement Of A Prescription 

    None 

    Money-Back Guarantee 

    365-day money-back guarantee 

    Pricing 

    $34.95 

    Onnit Alpha Brain is an excellent Adderall alternative that regulates anxiety levels and prevents mood swings. Additionally, it reduces instances of depressive episodes and promotes brain cell growth. It is also an excellent way to improve focus and concentration. 

    Onnit Alpha Brain is intended to reduce inflammation in the brain. Research has demonstrated that when a person sustains a head injury, the immune system responds to the pain by activating the immune cells. However, they fail to complete the task they were given and exacerbate the inflammation. In such a situation, an organic supplement like Onnit Alpha Brain can help reduce this brain inflammation and promote healing. 

    Some benefits of using Onnit Alpha Brain are: 

    Regulates Healthy Brain Cells 

    Onnit Alpha Brain is a brain health supplement that uses natural ingredients like CoQ10 and Magnafolate to support brain cells and protect against age-related cognitive decline. These nutrients are involved in energy production, making them ideal for keeping mental clarity and focus. 

    Additionally, they help scavenge free radicals and promote healthy inflammation levels, which is essential for maintaining healthy brain cells. 

    Can Lower The Chances Of Developing Alzheimer’s 

    Onnit Alpha Brain is a dietary supplement that contains folic acid, which has been shown to help reduce the chances of developing Alzheimer’s disease. A study published in the Journal of Alzheimer’s Disease showed that people who took a daily folic acid supplement had a lower risk of developing Alzheimer’s disease than those who did not. 

    Ranking Factors Considered While Reviewing The Best Adderall Alternatives 

    This section will look at the parameters employed to determine the top Adderall alternatives. 

    Transparency 

    The Adderall alternatives have maintained transparency which is very important for consumers. They have done this by ensuring that all product ingredients are listed on their labels. They have also provided contact information so consumers can contact them if they have any questions or concerns. Additionally, they have made sure to answer any questions that consumers may have about their products in a timely and professional manner. 

    Quality Assurance 

    If you’re seeking Adderall alternatives that have undergone quality assurance measures, our list has plenty of options. All of the Adderall alternatives on our list are sourced ethically and have undergone multiple quality checks. This means that you can be confident in their potency and safety. 

    Only the best will do when it comes to taking care of your health. With our Adderall alternatives, you can be sure that you’re getting high-quality products that will help you stay focused and energized. These products are perfect for those who need an extra cognitive boost to get through the day or a challenging project. 

    Honest Touted Benefits 

    Many Adderall alternatives on the market claim to offer similar benefits without side effects. However, many of these products do not live up to their claims. Our list of Adderall alternatives contains only those products that have been shown to provide tangible benefits for brain health, mental clarity, and ADHD symptoms. 

    Each product on our list has been carefully evaluated to ensure that it is effective and safe. We only recommend products with a proven track record of helping people improve their brain health and achieve their desired results. 

    If you are looking for an effective Adderall alternative that can help you improve your cognitive function and focus, we highly recommend trying one of the products on our list. 

    Brand Reputation 

    There are many Adderall alternatives available on the market, and it can be challenging to know which one to choose. Our list of Adderall alternatives includes only those with an excellent brand reputation and a proven safety track record. You can be confident that any options on our list will be a safe bet. 

    Scientifically Backed Ingredients 

    When finding a natural OTC Adderall alternative, looking for a product with scientifically-backed ingredients is essential. That way, you can ensure the product is reliable and will work effectively. The Adderall alternatives on our list all contain ingredients that have been proven to be effective in clinical trials. So, you can rest assured that these products will be effective in helping you improve your focus and concentration. 

    Customer Reviews 

    Customer reviews are critical when searching for the best natural Adderall alternatives. So, we have done the legwork for you and searched for the best products with many positive customer testimonials. Each natural OTC Adderall alternative on the list above has more than four stars rating, making them highly reliable. 

    In addition, the above Adderall alternatives have some of the best customer reviews, where users have raved about their efficacy in improving cognitive function. 

    Pricing And Money-Back Guarantee 

    If you’re looking for the best Adderall alternative that’s reasonably priced and has an excellent money-back guarantee, then you’ll want to refer to our list. These options are worth investments, as they’ll help boost your productivity and focus without breaking the bank. Plus, if you’re unsatisfied with the results, you can always get your money back. So why not give them a try? 

    Third-Party Lab Testing 

    Each of the top Adderall alternatives on our list has been third-party lab tested. This means that an independent, unbiased organization has looked at the product and confirmed that it meets specific standards. This is important because it helps to ensure that the product is safe and effective. 

    Third-party lab testing can also give insight into how a product works. For example, we can see if a particular ingredient is present in the formula and whether or not it is effective. This information can help us make informed decisions about which products suit us. 

    Ultimately, third-party lab testing is a valuable tool to help us choose the best products for our needs. 

    What Are The Side Effects Of Taking Adderall? 

    The side effects of long-term usage of Adderall can be severe and potentially life-threatening. Common side effects include increased heart rate and blood pressure, insomnia, anxiety, irritability, depression, and even psychosis. Additionally, long-term use of Adderall can lead to physical dependence and addiction. 

    Long-term use of Adderall can also cause changes in the brain’s chemistry that may decrease dopamine levels, leading to anhedonia (inability to feel pleasure), fatigue, apathy, and difficulty concentrating. It can also cause changes in appetite leading to weight loss or gain. Other potential side effects include headaches, stomach pain, nausea, vomiting, dry mouth, dizziness, or lightheadedness. 

    In addition to these physical side effects, long-term use of Adderall can also have psychological effects, such as paranoia or hallucinations. It is important to note that these side effects are not experienced by everyone who takes Adderall; however, they are possible risks associated with its long-term use. Therefore, individuals taking this medication must be aware of the potential risks and discuss them with their doctor before starting treatment. 

    Why Should You Use Natural Supplements Instead Of Adderall? 

    Adderall is a powerful stimulant medication used to treat attention deficit hyperactivity disorder (ADHD) and narcolepsy. While it can effectively treat these conditions, it also has a high potential for abuse and addiction. 

    Additionally, long-term use of Adderall can lead to physical dependence and severe side effects such as increased heart rate and blood pressure, insomnia, anxiety, irritability, depression, and even psychosis. For these reasons, many people are looking for alternatives to Adderall that are safer and more natural. 

    Natural supplements are an excellent alternative to Adderall because they provide the same benefits without the risk of addiction or serious side effects. 

    Natural supplements typically contain herbs, vitamins, minerals, amino acids, and other plant extracts that have been shown to improve focus and concentration without the risk of addiction or serious side effects. 

    These ingredients work together to help improve cognitive function while providing essential nutrients that support overall health. Natural supplements do not require a prescription, so they are much easier to obtain than Adderall. 

    In addition to being safer than Adderall, natural supplements can be more effective in treating ADHD symptoms. Studies have shown that certain natural supplements, such as NeuroTonix, can be just as effective in treating ADHD symptoms as Adderall. 

    Common Ingredients In The Best Adderall Alternatives Backed By Science 

    In this section of our review, we shall discuss some of the common ingredients in the supplements listed above and examine the research behind them so you can make an informed decision about a natural alternative to Adderall. 

    Maritime Pine Bark 

    Maritime pine bark, also known as Pinus pinaster, is a pine tree native to the Mediterranean region. It has been used for centuries in traditional medicine to treat various ailments, including inflammation and cardiovascular diseases. 

    More recently, it has been studied for its potential benefits on brain health. Research suggests that maritime pine bark may help improve focus and concentration by increasing blood flow to the brain and providing antioxidants that protect against oxidative stress. 

    The active ingredient in maritime pine bark is pycnogenol, a powerful antioxidant that helps reduce inflammation and protect cells from damage caused by free radicals. 

    Pycnogenol also increases nitric oxide levels in the body, which helps relax blood vessels and increase blood flow to the brain. This increased blood flow can help improve cognitive function, including focus and concentration. 

    Additionally, pycnogenol has been shown to reduce symptoms of anxiety and depression, which can further help focus and concentration. 

    Rhodiola Rosea 

    Rhodiola Rosea has been used in traditional medicine as an adaptogen for centuries. Adaptogens are plant-based therapies that help the body cope with stress and promote overall well-being. This herb is often referred to as “golden root” because it positively affects focus, concentration, and brain health. 

    Rhodiola Rosea has been seen to enhance both short-term and long-term memory and improve cognitive performance in general. In one experiment, volunteers were given either a placebo or a supplement containing 200 mg of Rhodiola Rosea extract—those who took the active supplement displayed significant improvements in their analytical skills compared to the placebo group. 

    A study on university students showed that taking a supplement containing 250mg of Rhodiola Rosea improved physical energy levels. The herb also helped boost alertness and concentration, enhance intellectual task performance, and reduce fatigue symptoms. 

    Saw Palmetto 

    Saw palmetto is an herbal supplement derived from the berries of a small palm tree native to North America. It has been used for centuries as a natural remedy for various ailments, including prostate health and urinary tract infections. More recently, it has been studied for its potential benefits on brain health. 

    Saw palmetto works by inhibiting the enzyme 5-alpha reductase, which is responsible for converting testosterone into dihydrotestosterone (DHT). DHT is linked to hair loss and other conditions such as enlarged prostate and male pattern baldness. By blocking this enzyme, saw palmetto can help reduce levels of DHT in the body, which may lead to improved brain health. 

    Studies have shown that saw palmetto can improve focus and concentration by increasing blood flow to the brain and providing antioxidants that protect against oxidative stress. Additionally, saw palmetto has been seen to enhance both short-term and long-term memory and improve cognitive performance in general. 

    Saw palmetto makes for a great alternative to Adderall due to its natural characteristics of improving brain health without any side effects associated with Adderall use. 

    Ginkgo Biloba 

    Ginkgo biloba is an ancient herb from the oldest living tree species on Earth. It is native to Asia and has been used in Chinese and Ayurvedic medicine for centuries for its potential therapeutic properties. Extracts from its leaf have gained popularity as dietary supplements due to their high concentrations of antioxidant compounds, such as flavonoids and terpenoids. 

    Recent research suggests they can potentially help reduce inflammation, combat oxidative stress caused by free radicals, protect neurons, reduce blood clotting disorders – which can prevent heart attack or stroke – and even assist with memory loss related to aging. 

    Studies have also highlighted the cognitive-enhancing effects of Ginkgo biloba extracts. Several studies have found promising evidence that Ginkgo biloba can help improve focus, concentration, mental clarity, and overall cognition in healthy individuals. 

    It appears to enhance neuron communication in short-term memory processes (like learning new things) and long-term memory storage processes (like retaining information). 

    Ashwagandha 

    One of the main benefits of ashwagandha is that it boosts the body’s ability to retain information and therefore enhances memory recall. This can be especially helpful for students or people who work high-stress jobs or require intricate problem-solving skills. 

    In one study, researchers gave healthy subjects either an ashwagandha supplement or a placebo every day for eight weeks and asked them to do simple memory tests throughout the experiment. Those who took the supplement performed significantly better on all memory tests than those who took the placebo. 

    Moreover, stress and anxiety levels have been known to directly impact cognitive performance, such as concentration, focus, learning new things, reasoning skills, etc., as it often hinders creativity and disrupts our neural pathways. 

    Ashwagandha has been used in ayurvedic medicine to reduce stress levels in the mind and body by regulating hormone production, which results in improved cognition performance, such as faster decision-making skills, and boosts working memory capacities. 

    In one study by the University of Texas, scientists found that those who took ashwagandha extract over eight weeks had reduced their anxiety scores by 26{fe463f59fb70c5c01486843be1d66c13e664ed3ae921464fa884afebcc0ffe6c} compared to those taking a placebo pill. 

    GABA 

    GABA – short for gamma-Aminobutyric acid – is a powerful neurotransmitter that plays a vital role in many mental and physical health aspects, including improving focus, concentration, and overall brain health. 

    For example, hyperactivity is another common symptom of mild mental health issues like Attention Deficit Hyperactivity Disorder (ADHD). 

    Hyperactivity is characterized by excessive talking or fidgeting, which can impair your ability to focus and concentrate on tasks for long periods. 

    Fortunately, GABA has decreased hyperactivity related to ADHD, allowing people to manage their attention spans better and stay focused on the task. 

    Bacopa Monnieri 

    Bacopa Monnieri, also known as Brahmi, is an herbal medicinal plant used for centuries in Ayurvedic medicine. It is believed to help improve cognitive functions such as focus and memory. Recently, Bacopa Monnieri has become famous for its potential to enhance focus, concentration, and brain health. 

    Studies have also shown that taking Bacopa Monnieri can help improve focus and concentration by improving information processing speed and accuracy while supporting cognitive abilities such as memorizing facts. Data suggests that supplementing with the herb may help reduce distractions, enabling you to maintain your attention span and remain alert when needed. 

    Certain compounds found in Bacopa Monnieri have been linked with various potential brain health benefits, including improved neuronal communication and neuron generation in aging brains. This could further support learning skills and memory recall speeds and enhance creativity over time. 

    Lion’s Mane Mushroom 

    The Lion’s Mane mushroom is getting attention for its ability to intake and process information more quickly, providing a cognitive boost in the intensity of focus. The mushrooms contain compounds that can affect neurological functions such as memory formation, learning, and mental performance. 

    Studies have shown that Lion’s Mane mushroom components can help improve memory and reduce inflammation associated with age-related cognitive diseases like Alzheimer’s and dementia. 

    It contains a nerve growth factor that plays an essential role in the repair of neurons and helps generate healthy new cells within the brain. This is particularly beneficial for those who suffer from diseases like depression or Parkinson’s, which are highly correlated with the loss of neurons. 

    FAQs About Adderall Alternatives 

    Q: What Is Adderall? 

    A: Adderall is a psychostimulant drug used to treat attention deficit hyperactivity disorder (ADHD) and narcolepsy. The medication increases alertness, attention, and brain energy. 

    Adderall is a central nervous system (CNS) stimulant that belongs to the class of drugs known as amphetamines. The active ingredients in Adderall are amphetamine and dextroamphetamine, both powerful stimulants. 

    While Adderall is an effective treatment for ADHD and narcolepsy, it is not without risks. The most common side effects of Adderall include headaches, trouble sleeping, dry mouth, and weight loss. Some people may also experience more severe side effects such as heart problems, mental health problems, or addiction. 

    Q: What Is ADHD? 

    A: Attention Deficit Hyperactivity Disorder (ADHD) is a mental health disorder that affects millions of people around the world. 

    A combination of genetic and environmental factors causes ADHD. Research suggests that genetics play a role in the development of ADHD, as it tends to run in families. Environmental factors such as stress or trauma can also contribute to ADHD symptoms. 

    The symptoms of ADHD can be problematic for individuals because they can interfere with daily life activities such as schoolwork, work performance, relationships, and self-esteem. People with ADHD may struggle to stay organized or complete tasks on time due to difficulty concentrating or controlling their impulses. 

    Q: What Are The Symptoms Of ADHD? 

    A: Attention Deficit Hyperactivity Disorder (ADHD) is a mental health disorder that affects millions of people around the world. It is characterized by difficulty paying attention, hyperactivity, and impulsivity. People with ADHD may experience a range of symptoms, including: 

    • Inattention: People with ADHD often have difficulty focusing on tasks or activities for extended periods. They may be easily distracted and have trouble staying organized, following instructions, and completing tasks. They may also forget important details or make careless mistakes in their work. 

    • Hyperactivity: People with ADHD may fidget or squirm when seated, talk excessively, and have difficulty engaging in quiet activities. They may also feel restless and struggle to stay still for long periods. 

    • Impulsivity: People with ADHD often act without thinking first. This can lead to impulsive behaviors such as interrupting conversations, blurting out answers before questions are finished being asked, or making hasty decisions without considering the consequences. 

    • Emotional Dysregulation: People with ADHD may experience intense emotions such as anger or frustration more frequently than those without the disorder. They may also have difficulty regulating their emotions and managing stress effectively. 

    Q: Has the FDA Approved Adderall? 

    A: In short, the answer is yes. The U.S. Food and Drug Administration (FDA) has approved Adderall for treating attention deficit hyperactivity disorder (ADHD) and narcolepsy. 

    The FDA first approved Adderall in 1996 for treating ADHD in children ages three and older. In 2006, the FDA also approved Adderall for treating narcolepsy in adults and children ages six and older. 

    Q: What Are Natural OTC Adderall Alternatives? 

    A: Many people seek OTC Adderall alternatives because they either cannot get a prescription for Adderall or want to avoid its potential side effects. In a word, natural OTC Adderall alternatives are safe and effective Adderall substitutes. 

    Some of the most common ingredients in natural OTC Adderall alternatives include caffeine, omega-3 fatty acids, vitamin B, and Ginkgo Biloba. These ingredients increase blood flow to the brain, improve brain chemistry, and increase mental alertness. Some of these ingredients have been shown to improve overall cognitive performance, and research says that they are effective in treating ADHD symptoms as well. 

    Q: Are Natural Adderall Alternatives Safe? 

    A: There are several so-called “natural Adderall alternatives” on the market today. But are they safe? 

    Generally speaking, these natural alternatives are considered safe for most people. However, there are some exceptions where Adderall alternatives can have adverse effects. 

    For example, pregnant women and nursing mothers should avoid taking them. Adults taking other prescription medications may also want to avoid these supplements, as they could interact with them. Finally, anyone under 18 should also avoid taking natural Adderall alternatives because their bodies are still developing. 

    So while generally speaking, natural Adderall alternatives are safe, there are some exceptions that you should be aware of before taking them. 

    Q: How Long Does It Take For Adderall Alternatives To Work? 

    A: The length of time for a natural OTC Adderall alternative to work may vary from person to person. Some people may see results within a few weeks, while others may not see results for several months. The key is being patient and allowing the medication to work. Many see the best results after taking an Adderall alternative for 3-6 months. Results may vary, so you must talk to your doctor if you are not seeing the desired results after a few months of treatment. 

    Q: What Are The Health Benefits One Can Experience From A Natural OTC Adderall alternative? 

    A: One can experience several health benefits from an Adderall alternative. For instance, mental clarity, brain health, and brain cell regeneration are all possible with the right supplement. Additionally, those who have ADHD may find relief from symptoms by taking an Adderall alternative. 

    In addition to these benefits, many people report feeling more mentally alert and having reduced levels of brain fog after taking a supplement. Finally, research suggests that Adderall alternatives can help to reduce cognitive decline in older adults. 

    Q: Is Adderall Addictive? 

    A: Adderall is a prescription stimulant medication used to treat attention deficit hyperactivity disorder (ADHD) and narcolepsy. It contains two active ingredients, amphetamine, and dextroamphetamine, both central nervous system stimulants. These substances increase the neurotransmitters in the brain, such as dopamine and norepinephrine, which can help improve focus and concentration. 

    Although Adderall is not considered an addictive substance, it can be abused or misused in ways that can lead to addiction. People who take Adderall for non-medical reasons or at higher doses than prescribed may become dependent on the drug and experience withdrawal symptoms when they stop taking it. 

    This is because Adderall affects the reward pathways in the brain, leading to feelings of pleasure and satisfaction when taken. Over time, these feelings can become associated with taking Adderall, making it difficult for someone to stop using it without experiencing uncomfortable withdrawal symptoms. 

    Q: What Is A Schedule II Drug? 

    A: A Schedule II drug is a classification of drugs with a high potential for abuse and addiction. These drugs also have an accepted medical use, but the abuse potential is greater than that of Schedule III drugs. 

    Adderall is a Schedule II drug because it has a high potential for abuse and addiction. It is an amphetamine-based stimulant medication used to treat attention deficit hyperactivity disorder (ADHD) and narcolepsy. When taken as prescribed by a doctor, Adderall can be effective in treating these conditions. 

    However, when abused or taken without medical supervision, Adderall can cause serious side effects such as increased heart rate and blood pressure, insomnia, anxiety, irritability, depression, and even psychosis. Additionally, long-term use of Adderall can lead to physical dependence and addiction. For these reasons, it is classified as a Schedule II drug in the United States. 

    Q: Can The Best Adderall Alternatives Be Addictive? 

    A: There is a lot of debate about whether or not the best Adderall alternatives can be addictive. Some people believe they can be, while others think they cannot. The answer to this question honestly depends on the person taking the Adderall alternative. 

    However, if someone does not have a history of addiction, they may not be as likely to become addicted to a natural alternative to Adderall. It all comes down to the person and their personal history. 

    If someone has a history of addiction, they may be more likely to become addicted to an Adderall alternative and experience withdrawal symptoms. 

    Q: Can Adderall Alternatives Treat ADHD? 

    A: There are many Adderall alternatives on the market today that claim to be able to treat Attention Deficit Hyperactivity Disorder (ADHD). While some of these alternative treatments may help improve cognitive abilities and fix damaged brain cells and mental exhaustion, there is no assurance that they will treat ADHD. 

    However, our list of the best Adderall alternatives could potentially help treat ADHD. It’s essential to speak with a healthcare professional before starting any new treatment, as Adderall alternatives may not be suitable for everybody. 

    Q: What Are Some Of The Best Natural Alternatives to Adderall? 

    A: When searching for the best alternatives to Adderall, there are many things to remember and consider. However, you don’t have to worry anymore, as we have already found the best for you. Mind Lab Pro, Modafinil, NooCube Brain Productivity, Performance Lab Mind, and SANE Vitaae are some of the most effective alternatives to Adderall. 

    The Best Natural Adderall Alternatives for 2023 Final Verdict 

    Several people are resorting to alternatives to Adderall because this ADHD medication has multiple side effects. However, natural OTC Adderall alternatives can be consumed by other people who don’t necessarily have ADHD but want to improve their cognitive functioning. We vouch for the top five Adderall alternatives above that do not require any prescription. Go ahead and give them a try! 

    Affiliate Disclosure: 

    The links contained in this product review may result in a small commission if you opt to purchase the product recommended at no additional cost to you. This goes towards supporting our research and editorial team. Please know we only recommend high-quality products. 

    Disclaimer: 

    Please understand that any advice or guidelines revealed here are not even remotely substitutes for sound medical or financial advice from a licensed healthcare provider or certified financial advisor. Make sure to consult with a professional physician or financial consultant before making any purchasing decision if you use medications or have concerns following the review details shared above. Individual results may vary and are not guaranteed as the statements regarding these products have not been evaluated by the Food and Drug Administration or Health Canada. The efficacy of these products has not been confirmed by FDA, or Health Canada approved research. These products are not intended to diagnose, treat, cure or prevent any disease and do not provide any kind of get-rich money scheme. Reviewer is not responsible for pricing inaccuracies. Check product sales page for final prices. 

    Disclaimer: The above is a sponsored post, the views expressed are those of the sponsor/author and do not represent the stand and views of Outlook Editorial.

  • People With Cancer Should Be Wary of Taking Dietary Supplements

    People With Cancer Should Be Wary of Taking Dietary Supplements

    Jan. 19, 2023 – Cancer dietitian Lisa Cianciotta frequently finds herself sitting throughout from a affected individual who suddenly fishes a bottle of antioxidant dietary supplements from their bag and states, My pal advised me this will work truly perfectly,” or I browse on the world wide web that this is supposed to be actually very good for cancer.” 

    Though taking an antioxidant pill sounds harmless, Cianciotta, a scientific dietitian who performs with cancer clients at NewYork-Presbyterian Clinic in New York Metropolis, understands properly that this popular dietary health supplement can interfere with a patient’s radiation or chemotherapy.

    But several people with most cancers feel these about-the-counter nutritional vitamins, minerals, or natural remedies will support them, and most use at minimum a person nutritional dietary supplement alongside their most cancers treatment method.

    And that leaves Cianciotta with a fragile dialogue in advance of her. 

    Drug-dietary supplement interactions are sophisticated, usually varying by health supplement, most cancers, and treatment method form, and can do much more hurt than excellent. Common nutritional supplements may well, for instance, terminate the effects of a cancer therapy, earning it much less productive, or increase serious aspect results, this sort of as liver toxicity. But in other circumstances, supplementation, these kinds of as vitamin D for people who absence the vitamin, may possibly be advantageous, Cianciotta states. 

    These drug-supplement interactions can be difficult to pinpoint, supplied that a lot more than two-thirds of medical doctors you should not know their sufferers are using supplements.

    Here is what sufferers have to have to know about the prospective pitfalls of dietary supplement use through treatment method, and how oncologists can handle this thorny, frequently badly comprehended subject matter with clients.

    The Sophisticated Drug-Complement Landscape

    The listing of nutritional dietary supplements and how they can interact with different therapies and most cancers types is extended and nuanced. 

    But specific health supplements look to have an effect on most cancers therapies irrespective of other factors and need to be prevented. Any complement that strongly alters the body’s levels of the protein cytochromes P450 is one particular instance. This group of enzymes performs a critical job in metabolizing medicines, which include chemotherapy and immunotherapy brokers. 

    Specific health supplements – most notably St. John’s wort extract – might lessen or raise the activity of cytochrome P450, which can then  affect the concentrations of anticancer drugs in the blood, says William Figg, PharmD, an affiliate director of the Centre for Most cancers Investigation at the National Most cancers Institute in Bethesda, MD. Research display, for instance, that this widespread herbal supplement can maximize the activity of cytochrome P450, ensuing in reduced ranges of most cancers drugs.

    Outside of drug rate of metabolism, people with hormone-connected cancers, these as breast and prostate cancers, really should steer obvious of nutritional supplements that can alter ranges of testosterone or estrogen, Figg claims. The evergreen shrub ashwagandha, for example, is marketed to lower anxiety and tiredness, but can also boost testosterone concentrations – a probable issue for people with prostate most cancers receiving androgen deprivation remedy, which lowers testosterone stages. 

    Lots of oncologists counsel people versus employing antioxidant-based mostly dietary dietary supplements – notably turmeric and inexperienced tea extract – while they have radiation therapy and sure chemotherapies. These therapies work by developing an abundance of hugely reactive molecules identified as free radicals in tumor cells, which enhance pressure within just these cells, ultimately killing them off. Antioxidants, in idea, can neutralize this impact, states Skyler Johnson, MD, a radiation oncologist at the Huntsman Cancer Institute at the University of Utah, Salt Lake Metropolis.  Some scientific studies suggest that antioxidant supplements may well reduce the results of radiation and chemotherapy, although the proof is mixed.

    Some dietary dietary supplements, such as substantial-dose inexperienced tea extract and vitamin A, can trigger kidney or liver toxicity, and “several most cancers patients previously have compromised kidney or liver purpose,” suggests Jun J. Mao, MD, main of integrative drugs at Memorial Sloan Kettering Cancer Middle in New York City. Even herbs that will not interfere with how properly a most cancers drug operates, these as stevia, can enhance remedy-relevant aspect results, these kinds of as nausea and vomiting. 

    Yet another likely problem with dietary health supplements: It truly is virtually unattainable to know just what is actually in them. For instance, just previous year, the Fda sent virtually 50 warning letters to companies advertising dietary dietary supplements. The difficulty is that federal rules governing production are a lot less demanding for supplements than for drugs. As a outcome, some supplements comprise components not shown on the label. 

    A single historical example was the supplement Computer-SPES, a combine of 8 herbs, marketed to men with prostate cancer. The dietary supplement was recalled in 2002 right after specified batches were identified to comprise traces of prescription prescription drugs, together with diethylstilbestrol, ethinyl estradiol, warfarin, and alprazolam.

    To further complicate issues, some nutritional supplements can be helpful. Most clients with cancer “are malnourished and missing out on vitamins and minerals they could be acquiring from meals,” says Cianciotta.

    Clients are tested routinely for vitamin deficiencies and get nutritional supplements as needed, she suggests. Vitamin D and folic acid are two of the most prevalent deficiencies in this affected individual population. Vitamin D supplementation can increase outcomes in people who have acquired a stem cell transplant by aiding engraftment and rebuilding the immune method, whilst folic acid supplementation can assistance to elevate lower purple blood mobile counts and hemoglobin stages. 

    Even though she seldom sees vitamin toxicity, Cianciotta stresses that more is not generally greater and nutritional supplement use, even when it appears to be safe or warranted due to a deficiency, ought to be taken under supervision, and monitored meticulously by the patient’s treatment staff. 

    Bringing Nutritional supplement Use Into the Light-weight

    Also frequently, providers are unaware of a patient’s complement use. 

    A core purpose: Nutritional health supplements are normally touted as purely natural, which lots of clients equate with security, suggests Samantha Heller, a senior medical nutritionist at New York University Langone Health and fitness in New York City. 

    That implies individuals may perhaps not know a dietary supplement can act like a drug and interfere with their most cancers treatment method, and therefore may perhaps not see the importance of telling their health practitioner.

    Nevertheless, the promise of herbs, natural vitamins, and minerals can be alluring, and there are a lot of good reasons patients decide to partake. One particular big attraction: Dietary health supplements can enable some individuals truly feel empowered.

    “Most cancers is a ailment that takes absent a large amount of control from the specific. Having dietary supplements or herbs is a way to regain some sense of manage,” says Mao. 

    The phenomenon can also be cultural, he states. Some persons develop up using herbs and dietary supplements to stay wholesome or fight wellbeing woes.

    Force or tips from loved ones or good friends who may perhaps believe they are serving to a cherished one with their dietary suggestions may perhaps engage in a purpose as nicely. Buddies and household “can not prescribe chemo, but they can invest in herbs and supplements,” Mao claims. 

    Patients seeking larger manage more than their health and fitness or who experience high ranges of anxiousness may well be extra most likely to take suggestions from friends and family members or far more most likely to believe false or deceptive promises about the efficacy or protection of nutritional supplements, points out  medical oncologist William Dahut, MD, chief scientific officer for the American Cancer Society. 

    Furthermore, social media normally amplifies and normalizes this misinformation, notes Johnson. In a 2021 review published in the Journal of the National Cancer Institute, he and colleagues uncovered that one particular-third of the most preferred articles or blog posts on most cancers treatment method posted to social media in 2018 and 2019 contained phony, inaccurate, or misleading information and facts that was often destructive. 

    Some of the untrue statements centered on unproven, potentially unsafe herbal remedies, according to Johnson. These included “lung most cancers can be fixed with cannabis oil” and “golden-berries get rid of and stop most cancers.” 

    Supplied exaggerated promises of “cures,” some individuals may well keep their complement use underneath the radar out of worry they will be judged or criticized. 

    “Clinicians should stay away from building sufferers come to feel judged or telling folks not to go on the web to do their possess investigation,” Johnson says.                         

    Guiding patients, instead, to precise resources of on the internet facts could be one particular way to enable individuals really feel empowered, he suggests. Most cancers.gov and the Memorial Sloan Kettering Most cancers Center’s About Herbs database provide accessible and accurate information and facts on nutritional nutritional supplements and most cancers cure for equally wellbeing care experts and patients, he notes. 

    If a certain complement is not safe and sound all through cure, suppliers need to be equipped to demonstrate why, claims  Cianciotta. In a the latest analyze, 80{fe463f59fb70c5c01486843be1d66c13e664ed3ae921464fa884afebcc0ffe6c} of overall health care companies surveyed thought that interactions among herbals and drugs could be problematic, but only 15{fe463f59fb70c5c01486843be1d66c13e664ed3ae921464fa884afebcc0ffe6c} could demonstrate why. 

    “Being able to demonstrate why we are discouraging a particular supplement suitable now tends to be significantly much better been given than just telling a individual not to acquire some thing, for the reason that it is bad,” she claims. 

    Another key is listening carefully to sufferers to realize why they might be taking a specific supplement. Does the individual experience out of manage? Is nausea a challenge? 

    “Making it possible for clients to notify you why they are applying a specific complement will often reveal unmet requires or psychosocial challenges,” Mao states. This data can enable suppliers to advise an proof-primarily based choice, these kinds of as mindfulness meditation or acupuncture to manage stress.

    And if a affected person has acquired a dietary dietary supplement from very well-indicating household and friends?

    “Just telling a individual that a presented nutritional supplement is worthless or hazardous could create relatives stress,” suggests  Mao. 

    Instead, he suggests reframing the challenge. 

    “We want to have a much better knowing of how sufferers are tolerating chemo or immunotherapy before throwing other issues on top rated of it. Enable them know that now may perhaps just not be the right time to insert a supplement to the blend,” Mao claims. 

    The bottom line: “Sufferers want to perform an energetic job in their have treatment, and we want to help them do that in a safe way,” he suggests. 

  • US FDA considers regulating CBD in meals, supplements

    US FDA considers regulating CBD in meals, supplements

    Image shows hemp or cannabis tincture.— Unsplash
    Impression shows hemp or hashish tincture.— Unsplash

    The US Foods and Drug Administration (Food and drug administration) is investigating the protection of consuming cannabis-infused meals and nutritional dietary supplements, Wellbeing Information documented.

    According to officials, the Food and drug administration programs to provide well being recommendations for regulating the rising amount of cannabis products and solutions in the upcoming months.

    “We want to be very clear that the info on CBD position to serious pitfalls that need to be thought of. Hazards contain liver harm, hurt to the male reproductive technique, and side consequences, these types of as alterations in alertness and other signs or symptoms,” Kristi Muldoon-Jacobs, Deputy Business office Director, Office environment of Foodstuff Additive Security said to the Food and drug administration in a report.

    Food and drug administration authorities are still seeking into more hashish and CBD-connected difficulties, these as how it can affect fertility and pregnancy.

    In 2018, Congress approved the usage of hemp but it remaining the Fda in cost of regulating hashish. Though some jurisdictions have founded their possess cannabis laws, other producers of items like CBD oil have introduced items without any very clear legal guidelines.

    Large amounts of CBD are discovered in hemp plants. While Tetrahydrocannabinol (THC) and CBD are comparable, CBD isn’t really normally imagined to have the similar intoxicating consequences on the brain and system as THC.

    The Food and drug administration warns that CBD and other medications may perhaps interact negatively. If utilized along with CBD, various medicines, which includes some antidepressants and painkillers, could drop their efficacy.

    The Food and drug administration has not but approved the use of cannabis-derived items as foodstuff or dietary supplements as opposed to pharmaceuticals. Aside from treating some significant seizure issues in individuals two decades of age and more mature, the authorities has not licenced companies to offer cannabis solutions for the treatment of any condition or issue.

    The drug’s title is Epidiolex and study has revealed that when utilised as directed by a doctor, the advantages outweigh the risks for the meant inhabitants.

    At this time, a organization ought to carry out clinical trials to demonstrate the therapeutic rewards of its hashish product or service.

    The sector is even now expanding immediately, while. According to a the latest examine by a cannabis info enterprise, international cannabis revenue may possibly rise from $30 billion in 2021 to $57 billion by 2026.

    The National Institute of Wellness of Usa states that hashish investigate is however in its infancy. Whilst some research indicates that cannabis-dependent medications may possibly cut down pain, other studies suggest that CBD could be harmful to some people today.

    The Food and drug administration intends to existing restrictions for legal cannabis solutions right after reviewing additional research. Some of the regulations could possibly phone for supplemental legislation from Congress.

    Medications, medical devices, nutritional nutritional supplements, and meals like toddler formulation are all matter to Food and drug administration regulation. A short while ago, the agency commenced maintaining tabs on the production, sale, and marketing and advertising of tobacco products and solutions.

    The agency’s analysis, in accordance to officials, is sophisticated by novel cannabis compounds like Delta-8, which has been out there on the market place for a even though. The recently learned cannabinoid is legal cannabis, but unlike CBD, it has intoxicating qualities.

    “Data on CBD details to true pitfalls, and the Fda is particularly concerned about the threats to kids, people who are pregnant or breastfeeding, and men and women taking other medications,” mentioned Muldoon-Jacobs, “Consumers should really be informed of the challenges and need to converse with a medical service provider about the use of any CBD products. We want persons to make knowledgeable selections about their health and fitness.”

  • FDA considers regulating cannabis compound CBD in foods, supplements over safety concerns

    FDA considers regulating cannabis compound CBD in foods, supplements over safety concerns

    H2o with nano-particles of Cannabidiol or CBD, derived from the Hashish plant, are shown on the shelf of a keep in Walnut Creek, California, April 26, 2019. (Picture by Smith Selection/Gado/Getty Visuals)

    The Food stuff and Drug Administration (Food and drug administration) is reportedly arranging to announce a regulatory framework for merchandise like CBD that are derived from authorized hashish in the coming months amid considerations about merchandise high-quality and security.

    CBD merchandise have proliferated in the several years considering that the enactment of the 2018 farm invoice legalized industrial hemp – a variant of the cannabis plant that lacks the intoxicating qualities of versions grown for usage as clinical or leisure marijuana. That opened the door for profits of CBD goods ranging from drinks and edible gummies to lotions and lotions that comprise no additional than .3{fe463f59fb70c5c01486843be1d66c13e664ed3ae921464fa884afebcc0ffe6c} THC, which is the cannabinoid chemical that can induce a large in users and is illegal at the federal degree inspite of legalization in 21 states.

    When asked for comment about the future regulatory plan, a spokesperson for the Food and drug administration offered Fox Business with a assertion by Food and drug administration Principal Deputy Commissioner Janet Woodcock, M.D., who is in cost of the agency’s initiatives to control hashish, that was also provided to the Wall Street Journal: “Supplied what we know about the basic safety of CBD so significantly, it raises issues for Fda about irrespective of whether these present regulatory pathways for food items and nutritional health supplements are correct for this substance. Food and drug administration is at the moment examining 3 Citizen petitions associated to this, and we strategy to react to them shortly.”

    Similar: Cannabis legislation by condition in 2022

    CBD products are generally touted as helping relieve agony, decrease stress and anxiety and endorse rest but can’t at this time be branded as dietary nutritional supplements or additional to meals products beneath Food and drug administration policies, and the agency has issued warning letters to many corporations about statements they’ve produced pertaining to their CBD products.

    The Fda is investigating the results of CBD in conjunction with the Nationwide Institutes of Wellness (NIH), and individuals conclusions will inform its recommendations about laws for people products and solutions. A analyze by NIH observed that a pharmaceutical-quality CBD merchandise identified as Epidiolex has served decrease seizures in clients with epilepsy around the age of 2, but it also prompted diarrhea, exhaustion and elevated liver enzymes in some little ones.

    At the time the Fda is ready to transfer ahead with building regulatory suggestions, it will have to come to a decision irrespective of whether CBD merchandise can be regulated as foods or dietary health supplements, instead than medicine, or if the agency will need to develop a new framework or phone upon Congress to enact a regulation on the topic.

    Mainly because cannabis crops include dozens of cannabinoid chemical substances, like THC and CBD, among others, new hashish items that emphasize recently found out cannabinoids current a challenge for regulators. 

    For instance, the most prevalent type of THC is identified as Delta-9, which has intoxicating houses and is unlawful at the federal amount. But Delta-8 THC can be derived from industrial hemp and falls into a authorized grey place in which it can be legally produced and marketed in spite of owning intoxicating qualities like its sister cannabinoid.

    Norman Birenbaum, an Food and drug administration senior adviser who formerly worked on cannabis regulation in New York and Rhode Island, told the Wall Road Journal that the agency has “developing and much more intensifying quick-expression fears” about these Delta-8 solutions right after a baby in Virginia died following having Delta-8 gummies while a quantity of other teens and kids ended up sickened in Texas and Iowa.

    The lack of a federal regulatory framework has provided rise to fears about purchaser safety and shortcomings in top quality assurance that may guide to THC being incorporated in some CBD goods meant to exclude it. It has also stored a range of organizations that ultimately prepare to enter this emerging marketplace on the sidelines thanks to authorized fears. Despite that hesitance, an Fda report from 2021 found that the CBD market place by itself was believed to be $4.6 billion final yr and forecasted it to quadruple by 2026.

    As the FDA’s regulatory process plays out, the U.S. Section of Agriculture’s laws on hemp production illustrate the difficulties of great-tuning procedures around the manufacturing and processing of cannabis solutions.

    A Congressional Investigate Company report identified that in 2021, hemp output was valued at $824 million throughout about 13,000 grower licenses all-around the place, and a dozen states had far more than 1,000 harvested acres of hemp in 2021 – led by Montana with 4,500 acres and Colorado with 3,100 acres. But the CRS report noted that about 20{fe463f59fb70c5c01486843be1d66c13e664ed3ae921464fa884afebcc0ffe6c} of hemp developed in a offered year will exceed the legal restrict of no far more than .3{fe463f59fb70c5c01486843be1d66c13e664ed3ae921464fa884afebcc0ffe6c} THC, which goes to exhibit the “inherent pitfalls to farmers of expanding hemp inside USDA’s regulatory framework.”

    GET UPDATES ON THIS Tale AT FOXBUSINESS.COM

     

  • 10 Natural Remedies and Supplements Proven by Science to Help Treat Anxiety

    10 Natural Remedies and Supplements Proven by Science to Help Treat Anxiety

    Worry Anxiety Artistic Concept

    Anxiety and panic attacks can be horrible. Fortunately, there are some herbal remedies and dietary supplements that may help according to scientific studies.

    More and more people in today’s world are struggling with stress and anxiety, especially in the wake of major public health scares like COVID-19.

    According to the National Alliance on Mental Illness, anxiety disorders are the most common mental health concern in the United States, with over 40 million adult Americans suffering from anxiety’s debilitating effect on their lives.[1]

    While there are many anti-anxiety prescription drugs on the market (oxazepam, lorazepam, paroxetine, midazolam, and chlordiazepoxide are just a few examples), these pharmaceutical products are often accompanied by unpleasant side effects or may result in chemical dependency.

    For this reason and others — such as cost — many consumers prefer to seek out alternative, natural treatments for their anxiety. But finding the right product for you can be a confusing and frustrating process.

    To make your search easier, here are 10 herbal remedies and dietary supplements proven by scientists to help with anxiety (however, always consult a doctor before taking any herbal remedy or dietary supplement):

    Omega-3 Food Sources

    Omega-3 fatty acids are known to be beneficial to heart health. They are also shown to have mental health benefits.

    Omega-3

    Omega-3 oils are polyunsaturated fatty acids (PUFAs) that are essential for building and maintaining a healthy body. Foods like oily fish are rich in these vital nutrients, hence omega-3 supplements are commonly derived from fish, such as cod liver oil.

    Besides helping to support the healthy development of the eyes, heart, bones, and joints, omega-3 has been shown to have mental health benefits too.

    In 2011, a randomized controlled trial sponsored by the US Department of Health’s National Center for Complementary and Integrative Health (NCCIH) found that medical students facing stressful exams who received daily omega-3 supplements experienced a 20 percent reduction in the symptoms of anxiety compared to those taking a placebo.[2]

    Ashwagandha

    There is evidence that ashwagandha root extract can provide a “significant” reduction in anxiety.

    Ashwagandha

    Withania somnifera, more commonly known as ashwagandha, is a small shrub whose roots have been widely used as a medicinal herb in Ayurveda (traditional Indian medicine) for centuries. Over recent years, a growing body of evidence for its healing properties has emerged from clinical trials.

    In 2012, an article published in the peer-reviewed Indian Journal of Psychological Medicine claimed that test subjects suffering from chronic stress experienced a “significant” reduction in anxiety after 60 days of taking a 300mg dose of ashwagandha root extract twice daily.[3] The authors concluded that the herb could “safely and effectively” be used to improve an individual’s resistance to stress.

    These findings were echoed in a more recent (2019) study, in which it was also found that participants receiving ashwagandha root extract enjoyed a better quality of sleep than those on the placebo.[4]

    Tea With Chamomile

    Chamomile is well-known for its calming properties.

    Chamomile

    Chamomile is the common name for several daisy-like plants cultivated for their flowers, which have long been dried and brewed in hot water to make the popular bedtime beverage, chamomile tea. Known and loved by generations of herbal tea-drinkers for its calming effect, chamomile is now increasingly acknowledged by scientists as an effective treatment for anxiety.

    During a 5-year (2010-2015) study of the long-term effects of chamomile therapy for moderate to severe generalized anxiety disorder (GAD) at the University of Pennsylvania, subjects in the treatment group received 500mg capsules of chamomile extract 3 times daily, while the control group members were given placebos.[5] The study found that after just 8 weeks, chamomile produced a significant and “clinically meaningful” reduction in GAD symptoms.

    Passionflower

    Although passionflower looks pretty psychedelic, studies have shown it to have anti-anxiety benefits.

    Passionflower

    Passionflower or Passiflora is a flowering vine native to the Americas, easily recognizable by its distinctive corona, which is typically purple, yellow, and white. Aside from its celebrated ornamental value, however, passionflower is coming to be known as a natural alternative to anti-anxiety medications.

    According to the results of a clinical trial published in the peer-reviewed Journal of Clinical Pharmacy and Therapeutics in 2001, Passiflora extract was just as effective as the anxiolytic drug oxazepam in treating generalized anxiety disorder (GAD), but had the additional benefit of not causing the impairment of job performance observed in patients taking oxazepam.[6]

    In a more recent study, the results of which were published in 2017, the anxiety-reducing effects of Passiflora incarnata (purple passionflower) were found to be similar to those of midazolam in patients undergoing a tooth extraction procedure, but without the adverse side effect of memory loss.[7]

    Skullcap Flowers (Scutellaria lateriflora)

    American skullcap (Scutellaria lateriflora) is known as a mild sedative.

    American Skullcap

    There are many varieties of skullcap — a flowering plant of the mint family, named for its helmet-shaped flowers — but American skullcap (Scutellaria lateriflora), used as a mild sedative in traditional herbal medicine for more than 200 years, is showing the most promise as a treatment for anxiety in clinical trials.

    In 2003, the peer-reviewed journal Alternative Therapies in Health and Medicine published the findings of a double-blind, placebo-controlled investigation into the efficacy of American skullcap in healthy volunteers, which “demonstrated noteworthy anxiolytic effects.”[8]

    Researchers at the University of Westminster in the UK have also noted — in a 2010 article for the British Journal of Wellbeing — that ongoing clinical and in vitro research is providing “encouraging support” for American skullcap as a “safe, well-tolerated and effective alternative” to pharmaceutical anxiolytics.[9]

    Lavender Flowers

    Research indicates that lavender oil has the potential to treat treat generalized anxiety disorder, and lavender scent can reduce anxiety and improve mood.

    Lavender

    Lavender is a flower well-known for its distinctive purple hue and pleasant fragrance, for which it is widely used in cooking and cosmetics. The essential oil distilled from the flower, lavender oil, is a popular choice for aromatherapists, as it has been believed since ancient times to have soothing properties. Modern scientific research has largely validated this belief.

    The results of two randomized controlled trials, published in 2010[10] and 2014[11] respectively, indicate that Silexan — a lavender oil preparation manufactured for oral use — is at least as effective as lorazepam (a benzodiazepine) and paroxetine (an SSRI), both drugs used to treat generalized anxiety disorder (GAD).

    Other studies indicate that ambient odors of lavender reduce anxiety and improve mood in dental waiting rooms (Physiology & Behavior, 2005),[12] and that lavender herbal tea has a similar calming effect in elderly patients (Complementary Therapies in Medicine, 2020).[13]

    Black Horehound

    Evidence suggests that the herb black horehound can help people with general anxiety disorder.

    Black Horehound

    Black horehound is a nettle-like perennial herb native to the Mediterranean and Central Asia, but can also be found growing throughout Europe and North America. Sometimes known as “Stinking Roger,” it is noted for its pungent odor. Despite its unpleasant smell, black horehound has been cultivated for medicinal use since at least the 13th century.

    The European Scientific Cooperative on Phytotherapy (ESCOP) — an umbrella organization comprising national herbal medicine councils and phytotherapy societies across Europe that compiles scientific data on herbal remedies for submission to the European Medicines Agency — reports that an open clinical study of black horehound “demonstrated a responder rate of 65{fe463f59fb70c5c01486843be1d66c13e664ed3ae921464fa884afebcc0ffe6c} after 60 days of treatment in patients with general anxiety disorder,” further confirming the anxiolytic effects of the herb observed during earlier in vivo experiments with rodents.[14]

    Saffron Spice

    Saffron is a favored spice, but saffron supplements have also been found to reduce anxiety.

    Saffron

    Saffron is a crimson-colored spice derived from the saffron crocus flower, probably originating in Persia (Iran), which today produces 90 percent of the world’s saffron. Mainly used as a seasoning, saffron has begun to be studied for its mental health benefits.

    A 2011 study learned that the scent of saffron significantly reduced levels of cortisol (the stress hormone produced by the adrenal glands) in women, suggesting the spice’s possible application as a treatment for premenstrual syndrome (PMS).[15] Saffron supplements were also found in 2016 to have a positive impact on Beck Anxiety Inventory (BAI) scores among adult patients with anxiety after 12 weeks of use.[16]

    Pharmactive Biotech Products, a Spanish company, claims that its patented saffron-derived supplement, Affron, is “backed by 8 human clinical studies” that showed improved mood in healthy consumers with anxiety.[17] The results of these studies have been published in peer-reviewed academic journals, including Complementary Therapies in Medicine (2017)[18] and the Journal of Affective Disorders (2018).[19]

    Echinacea Flowers

    Although echinacea is commonly thought to provide cold and flu relief, research suggests it can also relieve symptoms of anxiety.

    Echinacea

    Echinacea, a genus of the daisy family, is more commonly known as a traditional cold and flu medicine, but new evidence suggests that it can also be used to relieve the symptoms of anxiety.

    A 2010 research paper in Phytotherapy Research, a peer-reviewed journal, presented evidence from three laboratory tests of anxiety that demonstrated “for the first time” echinacea’s “considerable anxiolytic potential” compared with chlordiazepoxide, a benzodiazepine.[20]

    Results from a later clinical trial, published in 2019, also found that echinacea root extract has “significant beneficial effects on anxiety in humans.”[21]

    Dried Valerian Root

    Valerian root is shown to help relieve nervous energy and help people fall asleep.

    Valerian

    The sweet-scented flowering herb valerian, native to Europe and Asia, derives its name from the Latin word “valere,” which means to be strong or healthy. Although most commonly sold as a natural sleeping aid, it is also thought to alleviate stress, and was widely used to treat British soldiers for post-traumatic stress disorder (PTSD, or “shell shock”) during both world wars.[22]

    Thanks to a recent 4-week electroencephalographic (EEG) study by Korean researchers, in which patients suffering from psychological stress were administered a 100mg dose of valerian root extract three times daily, valerian is known to have a positive, anxiolytic impact on brain activity.[23]

    The European Union’s Committee on Herbal Medicinal Products, which notes that clinical studies support the use of dry ethanol extracts from valerian “for relief of mild nervous tension,” has approved valerian as a remedy for mild anxiety.[24]

    Doctor Consultation

    Consult your physician before starting a new supplement or herbal remedy.

    Concluding Advice

    Herbal and other natural medicines have been safely used by humans to help cope with stress and anxiety for many centuries, but it’s always advisable to consult your medical doctor before taking any of the remedies or supplements listed above, especially if these may interact with medicines you are already taking, or you are pregnant, breastfeeding, or have a pre-existing medical condition.

    Furthermore, you should only ever buy herbal remedies and dietary supplements from manufacturers known to be compliant with regulations enforced by the US Food & Drug Administration (FDA) or the national regulatory agency in your country, and which contain only ingredients generally recognized as safe for human consumption.

    Always buy from trusted sellers, and always read the label. Diagnosing and treating yourself is very difficult, which is why you should see a doctor if you are experiencing physical or mental symptoms. Always consult your doctor before taking any remedies or supplements.

    Reference:

    1. nami.org/About-Mental-Illness/Mental-Health-Conditions/Anxiety-Disorders
    2. pubmed.ncbi.nlm.nih.gov/21784145/
    3. journals.sagepub.com/doi/10.4103/0253-7176.106022
    4. cureus.com/articles/25730-adaptogenic-and-anxiolytic-effects-of-ashwagandha-root-extract-in-healthy-adults-a-double-blind-randomized-placebo-controlled-clinical-study
    5. sciencedirect.com/science/article/abs/pii/S0944711316301891
    6. onlinelibrary.wiley.com/doi/abs/10.1046/j.1365-2710.2001.00367.x
    7. ncbi.nlm.nih.gov/pmc/articles/PMC5217504/
    8. pubmed.ncbi.nlm.nih.gov/12652886/
    9. westminsterresearch.westminster.ac.uk/item/9023w/american-skullcap-scutellaria-lateriflora-an-ancient-remedy-for-today-s-anxiety
    10. sciencedirect.com/science/article/abs/pii/S094471130900261X
    11. academic.oup.com/ijnp/article/17/6/859/691858
    12. sciencedirect.com/science/article/abs/pii/S0031938405002660
    13. sciencedirect.com/science/article/abs/pii/S0965229919316292
    14. escop.com/downloads/black-horehound/
    15. sciencedirect.com/science/article/abs/pii/S0944711310004071
    16. degruyter.com/document/doi/10.1515/jcim-2015-0043/html
    17. pharmactive.eu/ingredient/affron_r-improves-your-mood/
    18. sciencedirect.com/science/article/abs/pii/S0965229917300821
    19. sciencedirect.com/science/article/abs/pii/S0165032717327131
    20. onlinelibrary.wiley.com/doi/10.1002/ptr.3181
    21. onlinelibrary.wiley.com/doi/10.1002/ptr.6558
    22. theherbalacademy.com/sheltering-with-valerian/
    23. onlinelibrary.wiley.com/doi/10.1002/ptr.6286
    24. ema.europa.eu/en/medicines/herbal/valerianae-radix

  • Taking CBD with herbal supplements could cause severe heart symptoms

    Taking CBD with herbal supplements could cause severe heart symptoms

    A green fluorescent outlining of the heartShare on Pinterest
    Combining distinct organic nutritional supplements could guide to intense cardiac issues, a scenario research indicates. MEHAU KULYK/SCIENCE Image LIBRARY/Getty Photographs
    • Employing organic supplements, such as derivatives of hashish, is getting extra and more common.
    • Some nutritional supplements are effortless to get more than the counter and are not as highly controlled as other drugs.
    • A current case examine demonstrates that employing sure health supplements in excessive can direct to extreme heart challenges.

    People’s use of dietary supplements has improved in modern several years. A lot of supplements may possibly have a specified volume of overall health benefits, but as they are not regulated, individuals must also work out caution.

    A current scenario report printed in Heart Rhythm Case Reports demonstrates that the too much use of specified substances such as hemp oil could direct to significant cardiac troubles.

    Dietary supplements are easily readily available to people and can provide different wellbeing benefits. For instance, dietary supplements give extra of the substances identified in food items, such as certain natural vitamins or minerals.

    Contrary to drugs, the Food and Drug Administration (Fda) does not offer as substantially regulation for dietary dietary supplements.

    Dr. Edo Paz, cardiologist and vice president of Health-related at K Health, who was not associated in the examine, discussed the concern with supplements to Medical News Nowadays:

    Mainly because the Fda regulates health supplements in a different way than medications, the dietary supplements are not very well-examined, so the exact attributes and facet consequences are not very well regarded. You may well even see versions in the preparing based on the distributor and batch.”

    Dr. Paz reported he encourages his sufferers to keep away from dietary supplements, out of a lack of reliable info.

    “If they do prepare to use them, I do my finest to investigation the attainable aspect effects and drug-supplement interactions, but this is not constantly possible provided the lack of knowledge,” he extra.

    A couple examples of widespread health supplements involve calcium, vitamin D, garlic, and ginkgo. At times, dietary supplements are a mix of several compounds, such as the complement berberine, which might be beneficial in the improvement of heart troubles and gut wellbeing.

    The CBD industry

    A single group of nutritional supplements that have turn out to be quite popular is individuals derived from cannabis. A number of illustrations of hashish derivatives involve hemp oil and cannabidiol (CBD).

    Hemp oil has several likely gains, which includes encouraging lessen muscle mass rigidity and strain and soreness aid. Similarly, CBD may support with ache reduction and may well even help to reduce stress and anxiety.

    Now, the Food and drug administration has only accredited a single derivative of CBD oil for medicinal use, Epidiolex, which can be utilised to treat seizures. Various derivatives of cannabis are continue to accessible as health supplements, this means that people today can buy and use them without supervision from a health care skilled.

    The case report in issue examined one 56-calendar year-old female and her significant signs and symptoms that coincided with dietary supplement use. She seasoned episodes of syncope (fainting) and dizziness.

    On cardiac analysis, professional medical experts discovered that she experienced reduced blood stress and an irregular coronary heart rhythm named Torsade de Pointes. This distinct disturbance in heart rhythm can turn into lifetime threatening.

    She also professional a extended QTc, which suggests troubles with the heart’s electrical alerts. Extended QTc is frequently affiliated with Torsade de Pointes.

    Her magnesium degrees have been also low, and just after therapy with intravenous magnesium and saline fluids, her coronary heart rhythm stabilized. Her individual healthcare record was unremarkable. But she discovered that she had been getting hemp oil that contained each CBD and cannabigerol (CBG).

    She claimed to be getting it for stress-associated reasons and was using it at six instances the advised dose. She was also getting health supplements containing berberine.

    Medical doctors discontinued all of her dietary supplement use though she was in the healthcare facility. Following five times, her coronary heart rhythm returned to regular.

    Centered on facts from this individual and their review of information bordering these nutritional supplements, examine authors consider that these health supplements induced the patient’s QTc prolongation.

    Dr. Paz famous that the scenario confirmed “a scary side impact of natural health supplements.”

    “In this case, the patient employed a variety of nutritional supplements, which resulted in a cardiac electrical abnormality termed QT prolongation. The individual even made a feared and possibly fatal consequence of QT prolongation called Torsades de pointe, which can degenerate to unexpected cardiac loss of life,” he explained to MNT.

    Dr. Paz claimed that many thanks to the medical staff the cause of these outcomes was determined, and the electrical abnormality resolved following the client stopped having them.

    This specific circumstance examine examined nutritional supplement use in a person specific and the perhaps intense cardiac challenges that could follow. However, it is important to note that she took an extremely large volume of hemp oil.

    The patient was also having additional than 1 health supplement, so her heart difficulties probably cannot be strictly attributed to one particular of them.

    Pharmacology qualified Professor Gary Stephens from the College of Reading through, who was also not associated in the analyze, observed to MNT that more clinical trials with regards to the use of these health supplements had been essential simply because of the constrained data.

    We will need to perform controlled scientific trials with effectively described medicines of standardized composition,” he claimed.

    Nevertheless, Prof. Stephens also pointed out that he was not conscious of any adverse cardiovascular consequences ascribed to CBD in scientific trials.

    “I’m unfamiliar with berberine, but the authors stage out them selves that it has been documented to cause the cardiac aspect result in the title of the paper,” he included.

    Dr. Stephen Alexander with the University of Nottingham, and a cannabis qualified who was not associated in the examine, claimed persons really should use supplements cautiously.

    “I would not assume the use of CBD or hemp oil to have a widespread unfavorable impact on cardiovascular wellness, but it does underline the want to regard these brokers and to handle them seriously (somewhat than to exceed suggested doses or merge with other inadequately characterised supplements),” he told MNT.

    He explained the analyze highlighted the require for higher recognition and training about the use of dietary supplements, in unique those derived from cannabis.

    Disclaimer: Professor Gary Stephens has finished some consultancy function for Jazz Pharmaceuticals. Jazz Pharmaceuticals also acquired out the corporation GW Pharmaceuticals, the company behind the multiple sclerosis cure nabiximols, which was the 1st cannabis-dependent medication accredited in the U.K. Prof. Stephens has also obtained funding from GW Prescribed drugs. Dr. Stephen Alexander has been recruited to the Scientific Advisory Board of Jazz Prescribed drugs.