Herbal Remedies for Osteoporosis Are Safe and Effective: South Korean Research

Linda Rider

Osteoporosis, literally “porous bone,” is frequently named a silent condition simply because lots of people do not recognize they have it till they crack a bone. Just one in three girls and a person in five gentlemen above 50 will suffer a damaged bone due to osteoporosis, according to the Worldwide Osteoporosis Basis.

Treatments utilized by Western medicine to take care of osteoporosis usually lead to undesirable facet outcomes. There may well be an option, nonetheless. In recent several years, analysis by professionals in common Korean medication has demonstrated that organic drugs can handle osteoporosis securely and correctly, without having the side outcomes of Western remedies.

Osteoporosis is a advanced bone sickness characterised by small bone density and microstructural harm to bone tissue, ensuing in greater bone fragility and fracture susceptibility. Osteoporotic fracture is a frequent event among the center-aged and elderly people. Osteoporosis is characterized by significant morbidity, large mortality prices, and large health-related expenses.

Western medication works by using numerous sorts of drugs to deal with osteoporosis, with the principal cure method currently being estrogen and bisphosphonate treatment. Having said that, extended-term estrogen therapy can increase the chance of most cancersblood clots, and stroke. Bisphosphonate treatment is connected with atypical femur fractures,  jaw necrosis, hypocalcemia, and esophageal cancer.

Added to the listing of side effects are unpleasant brief-phrase aspect effects such as joint suffering, complications, indigestion, fever, and flu like signs.

In an job interview on Dec. 13, Lee Soo-chil, director of Myongji Korean Medicine Clinic in South Korea, spoke to The Epoch Moments about herbal therapies for osteoporosis.

Lee stressed that conventional Korean drugs can effectively treat osteoporosis without the need of unpleasant side outcomes. Organic remedy can boost the body’s means to develop and fix nutritious bones. Optimizing the internal body natural environment according to the individual’s condition—including the osteoblasts, osteoclasts, osteogenic signal transmitters such as intercourse hormones and growth hormones, as properly as the basic factors of the bones—will allow bones to repair by themselves.

Lee mentioned a range of remedies utilized by classic Korean medication to treat osteoporosis, together with h2o hyssop (bacopa monnieri), eucommia, deer antler, and cuscuta (frequently acknowledged as dodder). These treatment options improve the proliferation and differentiation of osteoblasts and bone marrow mesenchymal stem cells (BMSC). They improve the activity of alkaline phosphatase (ALP) and mineral development, stimulating bone growth, preserving osteoblasts and BMSC from apoptosis brought on by oxidative tension, and inhibiting the generation of osteoclasts and bone resorption to reach an anti-osteoporosis result.

Several other herbs have been highlighted by Korean scientists in latest years for their means to take care of osteoporosis.

In accordance to scientists at Seoul’s Kyung Hee College, animal scientific studies have demonstrated that extracts of the herbs Schisandra chinensis, Lyceum chinensis (which produces the goji berry), and Eucommia ulmoides can restore bone density and raise the focus of osteocalcin in the blood. Further more, they can restore collagen type 1 and bone development elements these as bone morphogenetic protein 2 (BMP2), and osteopontin (OPN), increasing osteoporosis. The scientists revealed their results in March 2021 in the Journal of Ethnopharmacology.

A exploration team which include scientists from Kyung Hee University and the Korean Institute of Herbal Medicine confirmed that the herb He Shou Wu (also identified as tuber fleece flower or Chinese knotweed) improves osteoporosis by inhibiting the action of osteoclasts that lead to the disorder. The influence of He Shou Wu steamed in black bean juice is especially considerable. The paper was posted on April 25, 2020, in Evidence-Based mostly Complementary and Alternate Medication.

In addition, a joint study by scientists at Seoul’s Jaseng Joint Backbone and Study Institute and the University of Seoul’s Normal Materials Exploration Middle has confirmed the anti-osteoporosis influence of the lively chemical—harpogoside—contained in the herb harpagophytum procumbens (also acknowledged as devil’s claw).

In experiments conducted in rats, the chemical improved bone formation as a result of osteoblast proliferation, alkaline phosphate hydrolase action, and photochemical stimulation in osteoblastic cells (MC3T3-E1) involving osteogenesis and regeneration. The compound also improved the expression of genes and proteins involved in protein synthesis. In addition, it considerably elevated the bone density of the femur. The paper was printed in the Journal of Normal Solutions on Jan. 20, 2017. It acquired the 2017 Arthur E. Schwarting Award from the American Society of Pharmacognosy in July 2018.

Lisa Bian

Lisa Bian is a Korea-based mostly writer for The Epoch Instances concentrating on Korean modern society, its lifestyle, and worldwide relations.

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